List of omics topics in biology

Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome).

An omicist is a scientist who studies omeomics, cataloging all the “omics” subfields.[1]

Omics.org is a Wiki that collects and alphabetically lists all the known "omes" and "omics."[2]

## List of topics

[edit]

-ome | Field of study
(-omics) | Collection of | Parent subject | Notes

|
|
|
|

Acetylome | Acetylomics[3] | complete set of proteins and their corresponding lysine residues that undergo acetylation | Molecular Biology |
Allergenome | Allergenomics[4] | Proteomics of allergens | Genetics |
Antibodyome | Antibodyomics | The complete set of antibodies present in an organism  | Immunology |
Archaeome | Archaeomics | The collective genetic material of microorganisms in archaeological samples  | Microbiology |
Bacteriome  | Bacteriomics  | Community of bacteria associated with a particular ecological niche or host organism  | Microbiology |
Bibliome | Bibliomics | Scientific bibliographic data |  |
Biointeractome | Biointeractomics | The complete set of molecular interactions within a biological system  | Molecular Biology |
Biome |  | The whole set of ecological community of organisms and environments  | Ecology |
Cellome | Cellomics |  | Cellular Biology |
Connectome | Connectomics | Structural and functional brain connectivity at different spatiotemporal scales | Neuroscience |
Cytome | Cytomics | Cellular systems of an organism | Cytology |
Editome |  | RNA editing sites |  |
Embryome | Embryomics | Cell lineages of embryonic cells, genes expressed and antigens present during development | Embryology |
Envirome | Enviromics | Gene related environment factors (envirome) |  |
Environmental DNA | Environmental omics | Sequencing of ambient DNA |  |
Epigenome | Epigenomics | Epigenetic modifications | Molecular genetics | Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, collectively known as the epigenome
Exposome (2005) | Exposomics | An individual's environmental exposures, including in the prenatal environment | Molecular genetics | A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture").[5]
Exposome (2009) |  | Composite occupational exposures and occupational health problems | Occupational safety and health | The proposers of this term were aware of the previous term as used above but proposed to apply the term to a new field.[6][7]
Exome | Exomics | Exons in a genome | Molecular Genetics |
Foodome | Foodomics | Food and Nutrition issues related to bioactivity, quality, safety and traceability of foods through the application and integration of advanced omics technologies to improve consumer's well-being, health, and confidence. | Nutrition | The term was first defined in 2009[8]
Genome | Genomics
(Classical genetics) | Genes
(DNA sequences/Chromosomes) | Genetics | "Genome" refers to the set of all genes in an organism. However, "genome" was coined decades before it was discovered that most DNA is "non-coding" and not part of a gene; thus, "genome" originally referred to the entire collection of DNA within an organism. Today, both definitions are used, depending on the context.[9]
Glycome | Glycomics | Glycans | Glycobiology |
Hologenome | Hologenomics | Genomes of community members (i.e., holobionts)  | Metagenomics |
Humeome | Humeomics | The chemical components of soil humus | Soil science |
Interferome | Interferomics | Interferons | Immunology | Also a database of the same name.[10]
Interactome | Interactomics | All interactions |  | The term "interactomics" is generally not used. Instead, interactomes are considered the study of systems biology.[11][12]
Ionome | Ionomics | Inorganic biomolecules | Molecular Biology |
Kinome | Kinomics | Kinases | Molecular Biology | Proteins that add a phosphate group
Lipidome | Lipidomics[13] | Lipids | Biochemistry |
Mechanome | Mechanomics | The mechanical systems within an organism |  |
Metabolome | Metabolomics | Metabolites |  | All products of a biological reaction (including intermediates)
Metagenome | Metagenomics | Genetic material found in an environmental sample | Molecular Biology | The genetic material is assumed to contain DNA from multiple organisms and therefore multiple genomes, hence the inclusion of the prefix meta-.
Metallome | Metallomics | Metals and metalloids |  |
Microbiome | microbiomics | Collection of microorganisms in another organism such as an animal | Microbiology |
Obesidome | Obesidomics | Obesity related proteins | Proteomics | Coined by Pardo et al., 2012.[14]
ORFeome | ORFeomics | Open reading frames (ORFs) | Molecular Genetics |
Organome | Organomics | Organ interactions | Cellular Signalling / Cell Signaling and Tissue Engineering | The study of crosstalk between organs using physiologically relevant in-vitro models
Parvome | Parvomics | Secondary metabolites | Biochemistry | Coined by Mark Martin and introduced by Julian Davies in 2008, referring to the Latin parvus for "small", and describing the "humungous microbial world of small (secreted) molecules of great structural diversity".[15] See also [16]
Pharmacogenetics | Pharmacogenetics | SNPs and their effect on pharmacokinetics and pharmacodynamics | Pharmacogenomics
Genomics |
Pharmacogenome | Pharmacogenomics | The effect of changes on the genome on pharmacology | Pharmacogenetics
Genomics |
Phenome | Phenomics | Phenotypes | Genetics |
Physiome | Physiomics | Physiology of an organism |  |
Phytochemome | Phytochemomics | Phytochemicals |  | The term has been coined by del Castillo et al., 2013, Food Research International, [1]. Phytochemomics is a comprehensive concept aimed to increase the knowledge of phytochemicals' bioactivity which is of growing importance in agricultural, food, medicine and cosmetic sciences
Proteome | Proteomics | Proteins | Molecular Biology |
Regulome | Regulomics | Transcription factors and other molecules involved in the regulation of gene expression | Molecular Biology |
Researchsome |  | Research areas covered by an individual researcher or institution | Research | Coined by Ivan Erill at the 2011 EBM meeting[17]
Secretome | Secretomics | Secreted proteins | Proteomics | Subset of the proteome consisting of proteins actively exported from cells.[18]
Speechome | Speecheomics | Influences on language acquisition |  | Coined by the Human Speechome Project[19]
Synthetome |  | A set of artificial genes in an organism | [20][circular reference] |
Transcriptome | Transcriptomics | All RNA molecules including mRNA, rRNA, tRNA and other ncRNAs | Molecular Biology |
Trialome | Medicine | Human interventional trials data from clinical trial registries extended with trial results and links to resulting publications  |  |
Toponome | Toponomics | Cell and tissue structure | Molecular Biology |
Virome | Viromics  | complete set of viruses  | Virology |
Volatilome | Volatilomics | complete collection of volatile metabolites | Biomarkers |

## Hierarchy of topics

[edit]

For the sake of clarity, some topics are listed more than once.

* Bibliome
* Connectome
* Cytome
* Editome
* Embryome
* Epigenome
* Methylome[21]
* Exposome
* Envirome[22]
* Toxome[23]
* Foodome
* Microbiome
* Sociome
* Genome
* Variome
* Exome
* ORFeome
* Transcriptome
* Proteome
* Kinome
* Secretome
* Chaperome
* Allergenome
* Pharmacogenome
* Regulome
* Hologenome
* Interactome
* Interferome
* Ionome
* Fluxome
* Membranome
* Metagenome
* Metallome
* Microbiome
* Moleculome
* Glycome
* Ionome
* Lipidome
* Metabolome
* Volatilome
* Metallome
* Proteome
* Acetylome
* Obesidome
* Organome
* Phenome
* Physiome
* Connectome
* Synaptome[24]
* Dynome[25]
* Mechanome
* Regulome
* Researchsome
* Toponome
* Trialome
* Antibodyome[26]

## References

[edit]

1. ^ Yadav SP. (2007). "The Wholeness in Suffix -omics, -omes, and the Word Om". J Biomol Tech. 18 (5): 277. PMC 2392988. PMID 18166670.
2. ^ "Error 403(Invalid User)".
3. ^ Wen, Siqi; Li, Jiajia; Yang, Jingru; Li, Biao; Li, Na; Zhan, Xianquan (2021). "Quantitative Acetylomics Revealed Acetylation-Mediated Molecular Pathway Network Changes in Human Nonfunctional Pituitary Neuroendocrine Tumors". Frontiers in Endocrinology. 12. doi:10.3389/fendo.2021.753606. ISSN 1664-2392. PMC 8546192. PMID 34712204.
4. ^ Yagami T, Haishima Y, Tsuchiya T, Tomitaka-Yagami A, Kano H, Matsunaga K.; Haishima; Tsuchiya; Tomitaka-Yagami; Kano; Matsunaga (2004). "Proteomic analysis of putative latex allergens". Int Arch Allergy Immunol. 135 (1): 3–11\. doi:10.1159/000080036. PMID 15286439. S2CID 35112557.3-11&rft.date=2004&rft_id=https://api.semanticscholar.org/CorpusID:35112557#id-name=S2CID&rft_id=info:pmid/15286439&rft_id=info:doi/10.1159/000080036&rft.au=Yagami+T,+Haishima+Y,+Tsuchiya+T,+Tomitaka-Yagami+A,+Kano+H,+Matsunaga+K.&rft.au=Haishima&rft.au=Tsuchiya&rft.au=Tomitaka-Yagami&rft.au=Kano&rft.au=Matsunaga&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">`{{cite journal}}`: CS1 maint: multiple names: authors list (link)
5. ^ Wild CP (2005). "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology". Cancer Epidemiol. Biomarkers Prev. 14 (8): 1847–50\. doi:10.1158/1055-9965.EPI-05-0456. PMID 16103423.1847-50&rft.date=2005&rft_id=info:doi/10.1158/1055-9965.EPI-05-0456&rft_id=info:pmid/16103423&rft.au=Wild+CP&rft_id=https://doi.org/10.1158%2F1055-9965.EPI-05-0456&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
6. ^ Faisandier, Laurie; De Gaudemaris, Régis; Bicout, Dominique J. (2009). "Occupational Health Problem Network : the Exposome". arXiv:0907.3410 [stat.ME].
7. ^ Faisandier, Laurie; Bonneterre, Vincent; De Gaudemaris, Régis; Bicout, Dominique J. (2009). "A network-based approach for surveillance of occupational health exposures". arXiv:0907.3355 [stat.ME].
8. ^ Cifuentes, A. (2009). "Food analysis and Foodomics". Journal of Chromatography A. 1216 (43): 7109. doi:10.1016/j.chroma.2009.09.018. hdl:10261/154212. PMID 19765718.
9. ^ "genome, n". Oxford English Dictionary. March 2008.[dead link‍]
10. ^ "Home". interferome.org.
11. ^ "Protein Snapshots". www.the-scientist.com. Archived from the original on December 2, 2008.
12. ^ Main Page – Interactomics Archived July 6, 2008, at the Wayback Machine
13. ^ Subramaniam S, Fahy E, Gupta S, Sud M, Byrnes RW, Cotter D, Dinasarapu AR, Maurya MR (2011). "Bioinformatics and Systems Biology of the Lipidome". Chemical Reviews. 111 (10): 6452–6490\. doi:10.1021/cr200295k. PMC 3383319. PMID 21939287.6452-6490&rft.date=2011&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383319#id-name=PMC&rft_id=info:pmid/21939287&rft_id=info:doi/10.1021/cr200295k&rft.aulast=Subramaniam&rft.aufirst=S&rft.au=Fahy,+E&rft.au=Gupta,+S&rft.au=Sud,+M&rft.au=Byrnes,+RW&rft.au=Cotter,+D&rft.au=Dinasarapu,+AR&rft.au=Maurya,+MR&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383319&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
14. ^ Pardo, Maria; Roca-Rivada, Arturo; Seoane, Luisa Maria; Casanueva, Felipe F. (2012). "Obesidomics: Contribution of adipose tissue secretome analysis to obesity research". Endocrine. 41 (3): 374–383\. doi:10.1007/s12020-012-9617-z. PMID 22434412. S2CID 20503653.374-383&rft.date=2012&rft_id=https://api.semanticscholar.org/CorpusID:20503653#id-name=S2CID&rft_id=info:pmid/22434412&rft_id=info:doi/10.1007/s12020-012-9617-z&rft.aulast=Pardo&rft.aufirst=Maria&rft.au=Roca-Rivada,+Arturo&rft.au=Seoane,+Luisa+Maria&rft.au=Casanueva,+Felipe+F.&rft_id=https://link.springer.com/article/10.1007%2Fs12020-012-9617-z&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
15. ^ Schaechter M (2014-05-15). "Of Terms in Biology: The Parvome". Small Things Considered. Retrieved 2020-04-21.
16. ^ Davies J, Ryan KS (2012). "Introducing the parvome: bioactive compounds in the microbial world". ACS Chemical Biology. 7 (2): 252–259\. doi:10.1021/cb200337h. PMID 22074935.252-259&rft.date=2012&rft_id=info:doi/10.1021/cb200337h&rft_id=info:pmid/22074935&rft.aulast=Davies&rft.aufirst=J&rft.au=Ryan,+KS&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
17. ^ (2011) "15th EBM PROGRAM" Archived 2016-01-26 at the Wayback Machine Evolutionary Biology Meeting at Marseilles. Retrieved December 14, 2011.
18. ^ Dov Greenbaum; Nicholas M. Luscombe; Ronald Jansen; et al. (2001). "Interrelating Different Types of Genomic Data, from Proteome to Secretome: 'Oming in on Function". Genome Research. 11 (9): 1463–1468\. doi:10.1101/gr.207401. PMID 11544189.1463-1468&rft.date=2001&rft_id=info:doi/10.1101/gr.207401&rft_id=info:pmid/11544189&rft.au=Dov+Greenbaum&rft.au=Nicholas+M.+Luscombe&rft.au=Ronald+Jansen&rft.au=Qian,+J&rft.au=Gerstein,+M&rft_id=https://doi.org/10.1101%2Fgr.207401&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
19. ^ BBC article on the Speechome Project
20. ^ Synthetome
21. ^ Carlson, Scott M.; Gozani, Or (2014-10-09). "Emerging technologies to map the protein methylome". Journal of Molecular Biology. 426 (20): 3350–3362\. doi:10.1016/j.jmb.2014.04.024. ISSN 1089-8638. PMC 4177301. PMID 24805349.3350-3362&rft.date=2014-10-09&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177301#id-name=PMC&rft.issn=1089-8638&rft_id=info:pmid/24805349&rft_id=info:doi/10.1016/j.jmb.2014.04.024&rft.aulast=Carlson&rft.aufirst=Scott+M.&rft.au=Gozani,+Or&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177301&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
22. ^ Huser, V.; Cimino, J. J. (2012). "Precision and Negative Predictive Value of Links between ClinicalTrials.gov and PubMed". AMIA Annual Symposium Proceedings. 2012: 400–408\. PMC 3540528. PMID 23304310.400-408&rft.date=2012&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540528#id-name=PMC&rft_id=info:pmid/23304310&rft.aulast=Huser&rft.aufirst=V.&rft.au=Cimino,+J.+J.&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540528&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
23. ^ Bouhifd, Mounir; Andersen, Melvin E.; Baghdikian, Christina; Boekelheide, Kim; Crofton, Kevin M.; Fornace, Albert J.; Kleensang, Andre; Li, Henghong; Livi, Carolina (2015-01-01). "The human toxome project". ALTEX. 32 (2): 112–124\. doi:10.14573/altex.1502091. ISSN 1868-596X. PMC 4778566. PMID 25742299.112-124&rft.date=2015-01-01&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778566#id-name=PMC&rft.issn=1868-596X&rft_id=info:pmid/25742299&rft_id=info:doi/10.14573/altex.1502091&rft.aulast=Bouhifd&rft.aufirst=Mounir&rft.au=Andersen,+Melvin+E.&rft.au=Baghdikian,+Christina&rft.au=Boekelheide,+Kim&rft.au=Crofton,+Kevin+M.&rft.au=Fornace,+Albert+J.&rft.au=Kleensang,+Andre&rft.au=Li,+Henghong&rft.au=Livi,+Carolina&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778566&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
24. ^ DeFelipe, Javier (2010-11-26). "From the Connectome to the Synaptome: An Epic Love Story". Science. 330 (6008): 1198–1201\. Bibcode:2010Sci...330.1198D. doi:10.1126/science.1193378. ISSN 0036-8075. PMID 21109663. S2CID 33348231.1198-1201&rft.date=2010-11-26&rft_id=https://api.semanticscholar.org/CorpusID:33348231#id-name=S2CID&rft_id=info:bibcode/2010Sci...330.1198D&rft.issn=0036-8075&rft_id=info:doi/10.1126/science.1193378&rft_id=info:pmid/21109663&rft.aulast=DeFelipe&rft.aufirst=Javier&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
25. ^ Kopell, Nancy J.; Gritton, Howard J.; Whittington, Miles A.; Kramer, Mark A. (2014-09-17). "Beyond the connectome: the dynome". Neuron. 83 (6): 1319–1328\. doi:10.1016/j.neuron.2014.08.016. ISSN 1097-4199. PMC 4169213. PMID 25233314.1319-1328&rft.date=2014-09-17&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169213#id-name=PMC&rft.issn=1097-4199&rft_id=info:pmid/25233314&rft_id=info:doi/10.1016/j.neuron.2014.08.016&rft.aulast=Kopell&rft.aufirst=Nancy+J.&rft.au=Gritton,+Howard+J.&rft.au=Whittington,+Miles+A.&rft.au=Kramer,+Mark+A.&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169213&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">
26. ^ Dimitrov, DS (May–Jun 2010). "Therapeutic antibodies, vaccines and antibodyomes". mAbs. 2 (3): 347–56\. doi:10.4161/mabs.2.3.11779. PMC 2881260. PMID 20400863.347-56&rft.date=2010-05/2010-06&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881260#id-name=PMC&rft_id=info:pmid/20400863&rft_id=info:doi/10.4161/mabs.2.3.11779&rft.aulast=Dimitrov&rft.aufirst=DS&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881260&rfr_id=info:sid/en.wikipedia.org:List+of+omics+topics+in+biology" class="Z3988">

* v
* t
* e

Genomics

Fields|

* Cognitive genomics
* Computational genomics
* Comparative genomics
* Functional genomics
* Genome project
* Human Genome Project
* Metagenomics
* Human Microbiome Project
* Oncogenomics
* Pangenomics
* Personal genomics
* Population genomics
* Sociogenomics
* Structural genomics

Bioinformatics|

* Biochip
* Cheminformatics
* Chemogenomics
* Connectomics
* Human Connectome Project
* Epigenomics
* Human Epigenome Project
* Glycomics
* Immunomics
* Lipidomics
* Metabolomics
* Microbiomics
* Nutrigenomics
* Paleopolyploidy
* Pharmacogenetics
* Pharmacogenomics
* Systems biology
* Toxicogenomics
* Transcriptomics

Structural biology|

* Proteomics
* Human proteome project
* Call-map proteomics
* Structure-based drug design
* Expression proteomics

Research tools|

* 2-D electrophoresis
* Mass spectrometer
* Electrospray ionization
* Matrix-assisted laser desorption ionization
* Matrix-assisted laser desorption ionization-time of flight mass spectrometer
* Microfluidic-based tools
* Isotope affinity tags
* Chromosome conformation capture

Organizations|

* DNA Data Bank of Japan (JP)
* European Molecular Biology Laboratory (EU)
* National Institutes of Health (USA)
* Wellcome Sanger Institute (UK)

* List
* Category

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