Measles hemagglutinin

Hemagglutinin

Identifiers
Organism| Measles virus (strain Edmonston)
Symbol| H
PDB| 2RKC
UniProt| P08362
| Search for

Structures| Swiss-model
Domains| InterPro

Measles hemagglutinin is a hemagglutinin produced by measles virus.[1][2][3]

It attaches to CD46 using a dead neuraminidase domain.[4][5]

## References[edit]

1. ^ Pan CH, Jimenez GS, Nair N, et al. (August 2008). "Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus". Clin. Vaccine Immunol. 15 (8): 1214–21. doi:10.1128/CVI.00120-08. PMC 2519314. PMID 18524884.
2. ^ Tahara M, Takeda M, Shirogane Y, Hashiguchi T, Ohno S, Yanagi Y (May 2008). "Measles virus infects both polarized epithelial and immune cells by using distinctive receptor-binding sites on its hemagglutinin". J. Virol. 82 (9): 4630–7. doi:10.1128/JVI.02691-07. PMC 2293038. PMID 18287234.
3. ^ Hashiguchi T, Kajikawa M, Maita N, et al. (December 2007). "Crystal structure of measles virus hemagglutinin provides insight into effective vaccines". Proc. Natl. Acad. Sci. U.S.A. 104 (49): 19535–40. Bibcode:2007PNAS..10419535H. doi:10.1073/pnas.0707830104. PMC 2148324. PMID 18003910.
4. ^ Colf, LA; Juo, ZS; Garcia, KC (December 2007). "Structure of the measles virus hemagglutinin". Nature Structural & Molecular Biology. 14 (12): 1227–8. doi:10.1038/nsmb1342. PMID 18026116. S2CID 40292.
5. ^ Nussbaum O, Broder CC, Moss B, Stern LB, Rozenblatt S, Berger EA (June 1995). "Functional and structural interactions between measles virus hemagglutinin and CD46". J. Virol. 69 (6): 3341–9. doi:10.1128/JVI.69.6.3341-3349.1995. PMC 189046. PMID 7745681.

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Viral proteins (early and late)

DNA|

| Herpes simplex
(linear ds-DNA)|

| VSPs:|

| capsid:|

* HHV capsid portal protein
* Herpesvirus glycoprotein B

|

VNPs:|

* vmw65
* ICP8
* ICP34.5
* ICP47

Hepatitis B
(circular partially ds-DNA)|

| antigenes / VSPs:|

* HBsAg
* HBcAg
* HBeAg

|

VNPs:|

* HBx
* Hepatitis B virus DNA polymerase

Epstein–Barr
(circular ds-DNA)|

| VSPs:|

* LMP-1
* LMP-2

|

VNPs:|

* EBNA-1
* EBNA-2
* EBNA-3

ncRNA:|

* EBER

Polyomaviridae
(SV40, MPyV, MCPyV, HaPyV)
(non-enveloped circular ds-DNA)|

| VSPs:|

| capsid:|

* VP1
* VP2 and VP3

|

VNPs:|

| oncoprotein:|

* STag
* MTag
* LTag (SV40 Tag)

|

* Agnoprotein

Vaccinia (linear ds-DNA)|

| VNPs:|

* B13R

|

Baculoviridae (circular ds-DNA)|

| VNPs:|

* Early 35 kDa protein

|

RNA|

| ds-RNA|

| Rotavirus
(Duplornaviricota)|

| VNPs:|

* NSP1
* NSP2
* NSP3
* NSP4
* NSP5
* NSP6

|

Rhinov., Polio, Hep A,
etc. (Pisuviricota)|

| VNPs:|

* VPg

|

ss-RNA
negative-sense
(Negarnaviricota)|

| Influenza virus|

| VSPs:|

| capsid:|

* matrix protein
* M1 protein
* viral envelope
* M2 protein

|

glycoprotein:|

* Influenza hemagglutinin
* Neuraminidase
* HA-tag

VNPs:|

* NS1

Parainfluenza|

| VSPs:|

| glycoprotein:|

* Parainfluenza hemagglutinin-neuraminidase

|

Mumps|

| VSPs:|

| glycoprotein:|

* Mumps hemagglutinin-neuraminidase

|

Measles|

| VSPs:|

| glycoprotein:|

* Measles hemagglutinin

|

RSV|

| VSPs:|

| glycoprotein:|

* Respiratory syncytial virus G protein

|

Zaire ebolavirus|

| VSPs:|

| capsid:|

* matrix protein
* VP40
* VP24

|

Indiana vesiculovirus|

| VSPs:|

| capsid:|

* matrix protein
* Vesiculovirus matrix proteins

|

ss-RNA
positive-sense|

| Hepatitis C
(Kitrinoviricota)|

| VSPs:|

* viral envelope
* E1
* E2

|

VNPs:|

* P7
* NS2
* NS3
* NS4A
* NS4B
* NS5A
* NS5B

SARS-CoV-2
(Pisuviricota)|

| VSPs:|

* viral envelope
* Spike
* Envelope
* Membrane
* Nucleocapsid

|

VNPs:|

* ORF1ab
* 3C-like protease (NS5)
* ORF3a
* ORF3b
* ORF3c
* ORF3d
* ORF6
* ORF7a
* ORF7b
* ORF8
* ORF9b

RT|

| Structure and genome of HIV|

| VSPs:|

* gag
* p24
* pol
* Integrase
* Reverse transcriptase
* HIV-1 protease
* env
* gp120
* gp41

|

VRAPs:|

* transactivators
* Tat
* Rev
* Vpr
* Nef
* Vif
* Vpu or Vpx

Multiple

*     * Rous sarcoma virus
* murine leukemia virus

| Fusion protein|

| oncoprotein:|

* Gag-onc fusion protein

|

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