Mycobacterium heidelbergense

Species of bacterium

Mycobacterium heidelbergense

Scientific classification
Domain:  | Bacteria
Kingdom:  | Bacillati
Phylum:  | Actinomycetota
Class:  | Actinomycetia
Order:  | Mycobacteriales
Family:  | Mycobacteriaceae
Genus:  | Mycobacterium
Species:  |

M. heidelbergense

Binomial name
Mycobacterium heidelbergense

Haas et al. 1998, ATCC 51253

Mycobacterium heidelbergense is a Gram-positive, nonmotile, acid-fast coccobacillus. It is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

## Description

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Dimensions: 0.5-0.8 μm x 2.0-3.0 μm

Colony characteristics: Smooth, dome-like and nonpigmented colonies on Löwenstein–Jensen medium at 35 °C (0.5–1 mm in diameter).

Physiology: Slow growth on Löwenstein–Jensen medium at 35 °C within 3–4 weeks, optimal growth at a range from 33 to 35 °C, but also growth at 30 and 37 °C, growth at neither 25 nor at 45 °C, susceptible to isoniazid, rifampicin and ethambutol, resistant to pyrazinamide and cycloserine

Differential characteristics: Differentiation from M. malmoense, (bearing a strong phenotypic resemblance to M. heidelbergense), by its wider range of susceptibility to antituberculous drugs, (including isoniazid), and by its inability to grow on Löwenstein–Jensen medium at 25 °C, differentiation of M. triplex from M. heidelbergense by its positive nitrate reduction test and by its characteristic HPLC profile (triple-mycolate pattern).

Pathogenesis occurs in cervical lymph nodes (lymphadenitis) in immunocompetent patients. Its biosafety level is not known. The type strain was first isolated from an immunocompetent paediatric patient with cervical lymphadenitis with recurrent fistula formation, in Heidelberg, Germany.[1] It is strain 2554/91 = ATCC 51253 = CIP 105424 = DSM 44471.

## References

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1. ^ Haas et al. 1997\. A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J. Clin. Microbiol. 35, 3203-3209.

## External links

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* Type strain of Mycobacterium heidelbergense at BacDive \- the Bacterial Diversity Metadatabase

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* t
* e

Mycobacteria (including Nontuberculous)

Slowly growing
(R1P=photochromogenic;
R2S=scotochromogenic;
R3N=nonchromogenic)|

| Long helix 18
(TKHGC)|

| M. tuberculosis group|

MTC
M. tuberculosis
M. bovis
M. africanum
M. microti
M. canettii
M. caprae
M. pinnipedii

MPM
R1P

M. marinum
R2S

M. pseudoshottsii
R3N

M. ulcerans
M. shottsii
M. ulcerans liflandii

Leprosy
M. leprae
M. lepraemurium
M. lepromatosis

R3N
other

M. lacus
M. kumamotonense

|

K/H groups|

| M. kansasii group|

MAC
R3N

M. intracellulare/M. avium
M. avium subp. paratuberculosis
M. chimaera
R2S

M. bohemicum

R1P

M. kansasii
R3N

M. gastri

R2S

M. nebraskense
M. seoulense
R3N

M. scrofulaceum

|

M. haemophilum group|

* M. haemophilum
* R2S
* M. szulgai
* R3N
* M. malmoense

M. gordonae group|

* R1P
* M. asiaticum
* R2S
* M. gordonae

M. conspicuum group|

* R2S
* M. conspicuum

Long helix 18
(other)|

| M. xenopi group|

* M. botniense
* M. shimoidei/M. xenopi
* M. heckeshornense
* M. hassiacum

|

M. celatum group|

* R2S
* M. cookii
* R3N
* M. branderi
* M. celatum

M. hiberniae group|

* M. terrae
* M. hiberniae
* M. nonchromogenicum/M. arupense

Short helix 18|

| M. simiae clade|

M. simiae group
R3N

M. genavense/M. triplex
M. florentinum/M. montefiorense
M. heidelbergense/M. parmense
M. simiae
R2S

M. lentiflavum

M. kubicae group
R3N

M. parascrofulaceum
R2S

M. palustre/M. kubicae

M. interjectum group
M. interjectum
M. saskatchewanense

|

M. intermedium group|

* M. intermedium

Ungrouped|

* M. triviale
* M. doricum
* M. tusciae
* M. arosiense

Rapidly growing/
Runyon IV|

| M. neoaurum group|

* M. mageritense
* M. wolinskyi

* M. canariasense
* M. cosmeticum
* M. diernhoferi
* M. hodleri
* M. frederiksbergense
* M. neoaurum

* M. brisbanense

* M. fluoroanthenivorans

|

F/T groups|

| M. fortuitum group|

* M. chitae/M. fallax/M. gadium

* M. rhodesiae
* M. houstonense

* M. neworleansense/M. boenickei/M. fortuitum/M. porcinum/M. senegalense

* M. septicum/M. peregrinum/M. alvei

* M. farcinogenes

|

M. vaccae group|

* M. obuense/M. gilvum/M. parafortuitum

* M. chlorophenolicum/M. chubuense
* M. psychrotolerans/M. sphagni
* M. aubagnense/M. mucogenicum/M. phocaicum

* AV
* M. aurum
* M. vanbaalenii
* M. vaccae
* M. austroafricanum
* M. pyrenivorans

* M. poriferae

M. smegmatis group|

* M. agri/M. thermoresistibile
* M. duvalii/M. flavescens
* M. monacense
* M. pulveris/M. conceptionense/M. moriokaense

* M. novocastrense/M. brumae/M. phlei

* M. confluentis/M. madagascariense

* M. smegmatis/M. goodii

M. chelonae group|

* M. komossense
* M. murale/M. tokaiense
* M. aichiense
* M. chelonae
* M. abscessus
* M. immunogenum
* M. massiliense
* M. bolletii

M. elephantis group|

* M. elephantis
* M. holsaticum

Taxon identifiers

Mycobacterium heidelbergense|

* Wikidata: Q6947038
* BacDive: 8485
* CoL: 44W4D
* EoL: 971600
* GBIF: 3225180
* IRMNG: 11299457
* ITIS: 963702
* LPSN: mycobacterium-heidelbergense
* NCBI: 53376
* Open Tree of Life: 39331

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