Narasin

Chemical compound

Pharmaceutical compound

Narasin

Clinical data
Other names| (4S)-4-methyl-salinomycin
AHFS/Drugs.com| International Drug Names
ATCvet code|

* QP51BB04 (WHO) QP51BB54 (WHO)

Identifiers

IUPAC name

* (2R)-2-[(2R,3S,5S,6R)-6-[(1S,2S,3S,5R)-5- [(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]-3,5-dimethyl-2-tetrahydropyranyl]butanoic acid

CAS Number|

* 55134-13-9 Y

PubChem CID|

* 65452

ChemSpider|

* 58911

UNII|

* DZY9VU539P

CompTox Dashboard (EPA)|

* DTXSID2046707

ECHA InfoCard| 100.122.892
Chemical and physical data
Formula| C43H72O11
Molar mass| 765.038 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* O=C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C(O)=O)([H])[C@@H](C)C[C@@H]5C)[C@H](CC)[C@@]1([H])O[C@@]2(O[C@@]3(CC[C@]([C@]4([H])O[C@@H](C)[C@@](O)(CC)CC4)(C)O3)[C@H](O)C=C2)[C@H](C)C[C@@H]1C

InChI

* InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1

* Key:VHKXXVVRRDYCIK-CWCPJSEDSA-N

(verify)

Narasin is a coccidiostat and antibacterial agent.[1][2] It is a derivative of salinomycin with an additional methyl group. Narasin is produced by fermentation of a strain of Streptomyces aureofaciens.[3]

## References

[edit]

1. ^ Gerhold RW, Fuller AL, Lollis L, Parr C, McDougald LR (March 2011). "The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites". Avian Diseases. 55 (1): 59–64\. doi:10.1637/9572-101310-Reg.1. PMID 21500637. S2CID 30943649.
2. ^ Fitzgerald PR, Mansfield ME (July 1989). "Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone". American Journal of Veterinary Research. 50 (7): 1056–1059\. PMID 2774323.
3. ^ Anadón A, Martínez-Larrañaga MR (2014). "Veterinary Drugs Residues: Coccidiostats". Encyclopedia of Food Safety. pp. 63–75\. doi:10.1016/B978-0-12-378612-8.00246-8. ISBN 9780123786135.

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