OR6M1

Protein-coding gene in the species Homo sapiens

OR6M1

Identifiers
Aliases| OR6M1, OR11-271, olfactory receptor family 6 subfamily M member 1
External IDs| HomoloGene: 107073; GeneCards: OR6M1; OMA:OR6M1 - orthologs
| Gene location (Human)

Chr.| Chromosome 11 (human)[1]

Band| 11q24.1| Start| 123,805,408 bp[1]
End| 123,806,349 bp[1]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* mucosa of transverse colon

* body of pancreas

* right lobe of liver

* rectum

* superior frontal gyrus

* placenta

n/a

More reference expression data
BioGPS| |

More reference expression data
| Gene ontology

Molecular function|

* signal transducer activity
* olfactory receptor activity
* G protein-coupled receptor activity

Cellular component|

* plasma membrane
* membrane
* integral component of membrane

Biological process|

* sensory perception of smell
* signal transduction
* detection of chemical stimulus involved in sensory perception of smell
* response to stimulus
* G protein-coupled receptor signaling pathway

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

390261

n/a

Ensembl| |

ENSG00000196099

n/a

UniProt| |

Q8NGM8

n/a

RefSeq (mRNA)| |

NM_001005325

n/a

RefSeq (protein)| |

NP_001005325

n/a

Location (UCSC)| Chr 11: 123.81 – 123.81 Mb| n/a
PubMed search| [2]| n/a
Wikidata
| View/Edit Human|

|

Olfactory receptor 6M1 is a protein that in humans is encoded by the OR6M1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

## See also

[edit]

* Olfactory receptor

## References

[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196099 - Ensembl, May 2017
2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ a b "Entrez Gene: OR6M1 olfactory receptor, family 6, subfamily M, member 1".

## Further reading

[edit]

* Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
* Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
* Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

## External links

[edit]

* OR6M1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

* v
* t
* e

G protein-coupled receptors: olfactory receptors

Class I
(fish-like receptors)|

| Family 51|

* A2
* A4
* A7
* B2
* B4
* B5
* B6
* D1
* E1
* E2
* F1
* F2
* G1
* G2
* H1
* I1
* I2
* L1
* M1
* Q1
* S1
* T1
* V1

|

Family 52|

* A1
* A4
* A5
* B2
* B4
* B6
* D1
* E1
* E2
* E4
* E5
* E6
* E8
* H1
* I1
* I2
* J3
* K1
* K2
* L1
* L2
* M1
* N1
* N2
* N4
* N5
* P1
* R1
* W1

Family 56|

* A1
* A3
* A4
* B1
* B4

Class II
(tetrapod specific receptors)|

| Family 1|

* A1
* A2
* B1
* C1
* D2
* D4
* D5
* E1
* E2
* E3
* F1
* F2
* G1
* I1
* J1
* J2
* J4
* K1
* L1
* L3
* L4
* L6
* L8
* M1
* N1
* N2
* Q1
* S1
* S2

|

Family 2|

* A1
* A2
* A4
* A5
* A7
* A12
* A14
* A25
* A42
* AE1
* AG1
* AG2
* AJ1
* AK2
* AP1
* AT4
* B2
* B3
* B6
* B8
* B11
* C1
* C3
* D2
* D3
* F1
* F2
* G2
* G3
* G6
* H1
* H2
* J1
* J2
* J3
* K2
* L2
* L3
* L5
* L8
* L13
* M2
* M3
* M4
* M5
* M7
* S2
* T1
* T2
* T3
* T4
* T5
* T6
* T8
* T10
* T11
* T12
* T27
* T29
* T33
* T34
* T35
* V1
* V2
* W1
* W3
* W5
* Y1
* Z1

Family 3|

* A1
* A2
* A3
* A4

Family 4|

* A5
* A15
* A16
* A47
* B1
* C3
* C5
* C6
* C11
* C12
* C13
* C15
* C16
* C45
* C46
* D1
* D2
* D5
* D6
* D9
* D10
* D11
* E2
* F3
* F4
* F5
* F6
* F15
* F16
* F17
* F21
* F29
* K1
* K2
* K3
* K5
* K13
* K14
* K15
* K17
* L1
* M1
* M2
* N2
* N4
* N5
* P4
* Q3
* S1
* S2
* X1
* X2

Family 5|

* A1
* A2
* AC2
* AK2
* AK3
* AN1
* AP2
* AR1
* AS1
* AT1
* AU1
* AY1
* B2
* B3
* B12
* B17
* B21
* BF1
* BU1
* C1
* D13
* D14
* D16
* D18
* F1
* H1
* H2
* H6
* H14
* H15
* I1
* J2
* K1
* K2
* K3
* K4
* L1
* L2
* M1
* M3
* M8
* M9
* M10
* M11
* P2
* P3
* R1
* T1
* T2
* T3
* U1
* V1
* W2

Family 6|

* A2
* B1
* B2
* B3
* C1
* C2
* C3
* C4
* C6
* C65
* C68
* C70
* C74
* C75
* C76
* F1
* J1
* K2
* K3
* K6
* M1
* N1
* N2
* P1
* Q1
* S1
* T1
* V1
* X1
* Y1

Family 7|

* A2
* A5
* A10
* A17
* C1
* C2
* D2
* D4
* E24
* G1
* G2
* G3

Family 8|

* A1
* B2
* B3
* B4
* B8
* B12
* D1
* D2
* D4
* G1
* G2
* G5
* H1
* H2
* H3
* I2
* J1
* J3
* K1
* K3
* K5
* S1
* U1

Family 9|

* A2
* A4
* G1
* G4
* I1
* K2
* Q1
* Q2

Family 10|

* A2
* A3
* A4
* A5
* A6
* A7
* AD1
* AG1
* C1
* D4
* G2
* G3
* G4
* G6
* G7
* G8
* G9
* H1
* H2
* H3
* H4
* H5
* J1
* J3
* J5
* J6
* K1
* K2
* P1
* Q1
* R2
* S1
* T2
* V1
* W1
* X1
* Z1

Family 11|

* A1
* G2
* H1
* H4
* H6
* L1

Family 12|

* D2
* D3

Family 13|

* A1
* C2
* C3
* C4
* C5
* C8
* C9
* D1
* F1
* G1
* H1
* J1

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