PXK

PX domain containing serine/threonine kinase

Identifiers
Symbol| PXK
Alt. symbols| FLJ20335, MONaKA
NCBI gene| 54899
HGNC| 23326
OMIM| 611450
RefSeq| NM_017771
UniProt| Q6ZN39
Other data
Locus| Chr. 3 p21.2
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Structures| Swiss-model
Domains| InterPro

PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene.[1][2]

## Function[edit]

PXK binds to the Na⁺/K⁺-ATPase beta-1 (ATP1B1) and beta-3 (ATP1B3) subunits and modulates both Na⁺/K⁺-ATPase enzymatic and ion pump activities.[2]

## See also[edit]

* PX domain

## References[edit]

1. ^ "Entrez Gene: PX domain containing serine/threonine kinase".
2. ^ a b Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB (August 2005). "MONaKA, a novel modulator of the plasma membrane Na,K-ATPase". J. Neurosci. 25 (35): 7934–43. doi:10.1523/JNEUROSCI.0635-05.2005. PMC 6725465. PMID 16135750.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

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