Peptidase inhibitor 16

Protein-coding gene in the species Homo sapiens

PI16

Identifiers
Aliases| PI16, CRISP9, MSMBBP, PSPBP, CD364, peptidase inhibitor 16
External IDs| MGI: 1921366 HomoloGene: 134317 GeneCards: PI16
| Gene location (Human)

Chr.| Chromosome 6 (human)[1]

Band| 6p21.2| Start| 36,948,263 bp[1]
End| 36,964,837 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 17 (mouse)[2]

Band| 17|17 A3.3| Start| 29,536,654 bp[2]
End| 29,549,567 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* gastric mucosa

* vena cava

* pancreatic ductal cell

* right coronary artery

* canal of the cervix

* trachea

* tibial nerve

* cardia

* left coronary artery

* body of tongue

| Top expressed in

* lip

* extraocular muscle

* ascending aorta

* aortic valve

* ankle

* esophagus

* sciatic nerve

* conjunctival fornix

* myocardium of ventricle

* intercostal muscle

More reference expression data
BioGPS| | n/a

| Gene ontology

Molecular function|

* peptidase inhibitor activity

Cellular component|

* extracellular region
* extracellular space

Biological process|

* negative regulation of peptidase activity
* negative regulation of cell growth involved in cardiac muscle cell development

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

221476

74116

Ensembl| |

ENSG00000164530

ENSMUSG00000024011

UniProt| |

Q6UXB8

Q9ET66

RefSeq (mRNA)| |

NM_001199159
NM_153370

NM_023734

RefSeq (protein)| |

NP_001186088
NP_699201

NP_076223

Location (UCSC)| Chr 6: 36.95 – 36.96 Mb| Chr 17: 29.54 – 29.55 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Peptidase inhibitor 16 is a protein that in humans is encoded by the PI16 gene. [5]

## References[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164530 \- Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024011 \- Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: Peptidase inhibitor 16". Retrieved 2017-10-07.

## Further reading[edit]

* Reeves JR, Xuan JW, Arfanis K, Morin C, Garde SV, Ruiz MT, Wisniewski J, Panchal C, Tanner JE (2005). "Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids". Biochem. J. 385 (Pt 1): 105–14. doi:10.1042/BJ20040290. PMC 1134678. PMID 15344909.
* Reeves JR, Dulude H, Panchal C, Daigneault L, Ramnani DM (2006). "Prognostic value of prostate secretory protein of 94 amino acids and its binding protein after radical prostatectomy". Clin. Cancer Res. 12 (20 Pt 1): 6018–22. doi:10.1158/1078-0432.CCR-06-0625. PMID 17062675.

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