Piperidine N-piperoyltransferase

Enzyme

piperidine N-piperoyltransferase

Identifiers
EC no.| 2.3.1.145
CAS no.| 126806-22-2
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
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PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, a piperidine N-piperoyltransferase (EC 2.3.1.145) is an enzyme that catalyzes the chemical reaction

(E,E)-piperoyl-CoA + piperidine  ⇌ {\displaystyle \rightleftharpoons } CoA + N-[(E,E)-piperoyl]-piperidine

Thus, the two substrates of this enzyme are (E,E)-piperoyl-CoA and piperidine, whereas its two products are CoA and [[N-[(E,E)-piperoyl]-piperidine]].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (E,E)-piperoyl-CoA:piperidine N-piperoyltransferase. Other names in common use include piperidine piperoyltransferase, and piperoyl-CoA:piperidine N-piperoyltransferase.

## References

[edit]

* Geisler JG, Gross GG (1990). "The biosynthesis of piperine in Piper nigrum". Phytochemistry. 29 (2): 489–492\. doi:10.1016/0031-9422(90)85102-L.

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Transferases: acyltransferases (EC 2.3)

2.3.1: other than amino-acyl groups|

* acetyltransferases: Acetyl-Coenzyme A acetyltransferase
* N-Acetylglutamate synthase
* Choline acetyltransferase
* Dihydrolipoyl transacetylase
* Acetyl-CoA C-acyltransferase
* Beta-galactoside transacetylase
* Chloramphenicol acetyltransferase
* N-acetyltransferase
* Serotonin N-acetyl transferase
* HGSNAT
* ARD1A
* Histone acetyltransferase
* P300/CBP
* NAT2

* palmitoyltransferases: Carnitine O-palmitoyltransferase
* CPT1
* CPT2
* Serine C-palmitoyltransferase
* SPTLC1
* SPTLC2

* other: Acyltransferase like 2
* Aminolevulinic acid synthase
* Beta-ketoacyl-ACP synthase
* Glyceronephosphate O-acyltransferase
* Lecithin—cholesterol acyltransferase

* Glycerol-3-phosphate O-acyltransferase
* 1-acylglycerol-3-phosphate O-acyltransferase
* 2-acylglycerol-3-phosphate O-acyltransferase
* ABHD5

2.3.2: Aminoacyltransferases|

* Gamma-glutamyl transpeptidase
* Peptidyl transferase
* Transglutaminase
* Tissue transglutaminase
* Keratinocyte transglutaminase
* Factor XIII

2.3.3: converted into alkyl on transfer|

* Citrate synthase
* Decylcitrate synthase
* Citrate (Re)-synthase
* Decylhomocitrate synthase
* 2-methylcitrate synthase
* 2-ethylmalate synthase
* 3-ethylmalate synthase
* ATP citrate lyase
* Malate synthase
* HMG-CoA synthase
* HMGCS2
* 2-hydroxyglutarate synthase
* 3-propylmalate synthase
* 2-isopropylmalate synthase
* Homocitrate synthase
* Sulfoacetaldehyde acetyltransferase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

Portal:

* Biology

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