Pyridoxal oxidase

Class of enzymes

pyridoxal oxidase

Identifiers
EC no.| 1.2.3.8
CAS no.| 76415-81-1
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
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PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, a pyridoxal oxidase (EC 1.2.3.8) is an enzyme that catalyzes the chemical reaction

pyridoxal + H2O + O2 ⇌ {\displaystyle \rightleftharpoons } 4-pyridoxate + (?)

The 3 substrates of this enzyme are pyridoxal, H2O, and O2, whereas its product is 4-pyridoxate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyridoxal:oxygen 4-oxidoreductase. This enzyme participates in vitamin B6 metabolism. It employs one cofactor, molybdenum.

## References

[edit]

* Hanly EW (1980). "Preliminary characterization and physical properties of pyridoxal oxidase activity from Drosophila melanogaster". Mol. Gen. Genet. 180 (2): 455–462\. doi:10.1007/BF00425862.
* Warner CK, Watts DT, Finnerty V (1980). "Molybdenum hydroxylases in Drosophila. I. Preliminary studies of pyridoxal oxidase". Mol. Gen. Genet. 180 (2): 449–453\. doi:10.1007/BF00425861.

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Aldehyde/oxo oxidoreductases (EC 1.2)

1.2.1: NAD or NADP|

* Aldehyde dehydrogenase
* Acetaldehyde dehydrogenase
* Long-chain-aldehyde dehydrogenase
* Mycothiol-dependent formaldehyde dehydrogenase

1.2.2: cytochrome|

* Formate dehydrogenase (cytochrome)

1.2.3: oxygen|

* Aldehyde oxidase

1.2.4: disulfide|

* Oxoglutarate dehydrogenase complex
* Pyruvate dehydrogenase
* Branched-chain alpha-keto acid dehydrogenase complex
* BCKDHA
* BCKDHB
* DBT
* DLD

1.2.7: iron–sulfur protein|

* Pyruvate synthase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

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