Pyrrole-2-carboxylic acid

Names
Other names

2-Mialine, 2-Minaline, Minalin, Minaline

Identifiers

CAS Number

* 634-97-9 Y

3D model (JSmol)

* Interactive image

Beilstein Reference

| 80825
ChEBI |

* CHEBI:36751

ChEMBL |

* ChEMBL509027

ChemSpider |

* 11963

DrugBank |

* DB02543

ECHA InfoCard | 100.010.202
EC Number |

* 211-221-9

Gmelin Reference

| 101562
KEGG |

* C05942

PubChem CID

* 12473

CompTox Dashboard (EPA)

* DTXSID50212813

InChI

* InChI=1S/C5H5NO2/c7-5(8)4-2-1-3-6-4/h1-3,6H,(H,7,8)

Key: WRHZVMBBRYBTKZ-UHFFFAOYSA-N

SMILES

* C1=CNC(=C1)C(=O)O

Properties

Chemical formula

| C5H5NO2
Molar mass | 111.100 g·mol−1
Appearance  | white solid
Melting point | 206 °C (403 °F; 479 K)
Hazards
GHS labelling:

Pictograms

Signal word

| Warning

Hazard statements

| H315, H319, H335

Precautionary statements

| P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references

Chemical compound

Pyrrole-2-carboxylic acid is an organic compound with the formula HNC4H3CO2H. It is one of two monocarboxylic acids of pyrrole. It is a white solid. It arises in nature by dehydrogenation of the amino acid proline.[1] It also arises by carboxylation of pyrrole.[2] The ethyl ester of this acid is readily prepared from pyrrole.[3]

## References

[edit]

1. ^ Thomas, Michael G.; Burkart, Michael D.; Walsh, Christopher T. (2002). "Conversion of L-Proline to Pyrrolyl-2-Carboxyl-S-PCP during Undecylprodigiosin and Pyoluteorin Biosynthesis". Chemistry & Biology. 9 (2): 171–184\. doi:10.1016/S1074-5521(02)00100-X. PMID 11880032.
2. ^ Wieser, Marco; Yoshida, Toyokazu; Nagasawa, Toru (2001). "Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase and its application". Journal of Molecular Catalysis B: Enzymatic. 11 (4–6): 179–184\. doi:10.1016/S1381-1177(00)00038-2.4–6&rft.pages=179-184&rft.date=2001&rft_id=info:doi/10.1016/S1381-1177(00)00038-2&rft.aulast=Wieser&rft.aufirst=Marco&rft.au=Yoshida,+Toyokazu&rft.au=Nagasawa,+Toru&rfr_id=info:sid/en.wikipedia.org:Pyrrole-2-carboxylic+acid" class="Z3988">
3. ^ Denis M. Bailey, Robert E. Johnson, and Noel F. Albertson (1971). "Ethyl Pyrrole-2-Carboxylate". Organic Syntheses. 51: 100. doi:10.15227/orgsyn.051.0100.`{{cite journal}}`: CS1 maint: multiple names: authors list (link)

*[CID]: Compound ID
*[EPA]: U.S. Environmental Protection Agency
*[H315]: H315: Causes skin irritation
*[H319]: H319: Causes serious eye irritation
*[H335]: H335: May cause respiratory irritation
*[P261]: P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
*[P264]: P264: Wash ... thoroughly after handling.
*[P271]: P271: Use only outdoors or in a well-ventilated area.
*[P280]: P280: Wear protective gloves/protective clothing/eye protection/face protection.
*[P302+P352]: P302+P352: IF ON SKIN: Wash with soap and water.
*[P304+P340]: P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
*[P305+P351+P338]: P305+P351+P338: IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
*[P312]: P312: Call a POISON CENTER or doctor/physician if you feel unwell.
*[P321]: P321: Specific treatment (see ... on this label).
*[P332+P313]: P332+P313: If skin irritation occurs: Get medical advice/attention.
*[P337+P313]: P337+P313: If eye irritation persists: Get medical advice/attention.
*[P362]: P362: Take off contaminated clothing.
*[P403+P233]: P403+P233: Store in a well ventilated place. Keep container tightly closed.
*[P405]: P405: Store locked up.
*[P501]: P501: Dispose of contents/container to ...