Right to withdraw

The right to withdraw is a concept in clinical research ethics that a study participant in a clinical trial has a right to end participation in that trial at will. According to ICH GCP guidelines, a person can withdraw from the research at any point in time and the participant is not required to reveal the reason for discontinuation.

## Children in research[edit]

When children participate in clinical research their parents or guardians must give assent for them to participate, but ethics dictate that even in this case it is best to get the consent of the research subject. Studies have shown that children participating in research have little understanding of the right to withdraw when they are presented with the option.[1][2]

## Biobanks[edit]

Withdrawal from participating in biobank research is problematic for many reasons, including the fact that participant's data is often de-identified to grant research participant privacy.[3]

## References[edit]

1. ^ Ondrusek, Nancy; Abramovitch, Rona; Pencharz, Paul; Koren, Gideon (1998). "Empirical examination of the ability of children to consent to clinical research". Journal of Medical Ethics. 24 (3): 158–65. doi:10.1136/jme.24.3.158. PMC 1377517. PMID 9650109.
2. ^ Edwards, Sarah J.L. (2005). "Research Participation and the Right to Withdraw". Bioethics. 19 (2): 112–30. doi:10.1111/j.1467-8519.2005.00429.x. PMID 15943021.
3. ^ Eriksson, Stefan; Helgesson, Gert (2005). "Potential harms, anonymization, and the right to withdraw consent to biobank research". European Journal of Human Genetics. 13 (9): 1071–6. doi:10.1038/sj.ejhg.5201458. PMID 15986039.

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Research participant rights

Rights|

* Beneficence
* Justice
* Respect for persons
* Privacy for research participants
* Right to withdraw
* Return of results
* Informed consent

Human subject research|

* Clinical research
* Biobank
* Social research

Ethical systems|

* Research ethics
* Medical ethics
* Bioethics
* Clinical research ethics
* Biobank ethics

Guidelines for human subject research|

* List of medical ethics cases
* Nuremberg Code
* Declaration of Helsinki
* Belmont Report
* Common Rule

Monitoring in clinical trials|

* Ethics committee
* Institutional review board
* Data monitoring committee
* Community advisory board

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