Sphere Fluidics

British R&D company

Sphere Fluidics

Company type| Private
Founded| 2010; 14 years ago (2010)[1]
Headquarters| Cambridge, UK
Services| Research and Development
Website| spherefluidics.com

Sphere Fluidics is a Cambridge(UK)-based Life Sciences R&D company that specializes in biopharmaceutical discovery and development, cell therapy engineering, bioproduction and synthetic biology, analysis and isolation. The company is reported to own 25 patented products that include instruments, biochips, and specialist chemicals.[2][3]

## Overview[edit]

Sphere Fluidics was originally established in 2010, by two chemistry professors of Cambridge University, namely, Professor Chris Abell and Professor Wilhelm Huck, Dr. Frank F. Craig, an entrepreneur, and Dr. Maher Khaled, a Cambridge University Enterprise executive, as founders.[2][4][5]

## Funding[edit]

November 2021: Sphere Fluidics raised $40M led by Paris-based Sofinnova Partners and San Francisco-based Redmile Group.[6]

The total funds raised by Sphere Fluidics as of 2021, is reported to be, £46.7 million through various funding rounds, loans and grants.[6][4][3][5]

## Cyto-Mine Technology[edit]

Cyto-Mine is a patented single cell analysis and characterisation system by Sphere Fluidics. This technology is said to aid the development of biotherapeutics for treatment of cancer and inflammatory diseases and vaccine generation. Cyto-Mine is said to be an integrated device which can automatically perform single cell analysis, sorting, imaging and dispensing into individual wells of microtiter plates in a single compact system.[7][8][4]

## Developments and Partnerships[edit]

In 2019, Sphere Fluidics in partnership with Peak Analysis and Automation (PAA) introduced Integrated Microplate Handling and Single Cell Analysis Capabilities. The addition of S-LAB to the Cyto-Mine provides researchers with a further streamlined solution for single cell analysis in biopharmaceutical workflows.[9]

On 10 November 2021, Sphere Fluidics in partnership with ClexBio gave away 10 CYTRIX microfluidic hydrogel kits containing the novel CYTRIX hydrogel, Pico-Surf™ surfactant and Sphere Fluidics’ Pico-Gen™ double aqueous biochip, giving a plug-and-play system for microfluidic single-cell hydrogel encapsulation, marking the celebration of World Science Day for Peace and Development.[10]

## Awards[edit]

2013 : ACES Life Science Award[11][5]

2015: UK's top 50 disruptive SMEs by Real Business[12][13]

2017: European Product Innovation Award[2][14]

2020: Queen's Award for Enterprise for Innovation[15]

## References[edit]

1. ^ "Sphere Fluidics Limited Limited". Companies House. Retrieved 21 March 2021.
2. ^ a b c "Triple success for Cambridge life science pioneers | Business Weekly | Technology News | Business news | Cambridge and the East of England". www.businessweekly.co.uk. Retrieved 11 December 2017.
3. ^ a b "Sphere Fluidics wins $7 million for development of single cell analysis system - Cambridge Enterprise". Cambridge Enterprise. Retrieved 11 December 2017.
4. ^ a b c "Sphere Fluidics: biotherapeutics device attracts $7m investment - GOV.UK". www.gov.uk. Retrieved 11 December 2017.
5. ^ a b c "Re-inventing the test tube: Sphere Fluidics pioneers new approach to analysing cell samples | Science|Business". sciencebusiness.net. Retrieved 11 December 2017.
6. ^ a b biopharma-reporter.com. "Sphere Fluidics closes $40m funding round". biopharma-reporter.com. Retrieved 29 November 2021.
7. ^ "Sphere Fluidics, Geneva Biotech Receive €1.6M Grant to Develop DNA Cargo Delivery System". GenomeWeb. Retrieved 11 December 2017.
8. ^ "TTP Plc and Sphere Fluidics introduce Cyto-Mine Single Cell Analysis System". The Scientist. Retrieved 11 December 2017.
9. ^ "Sphere Fluidics and PAA Introduce Integrated Microplate Handling and Single Cell Analysis Capabilities". Lab Manager. Retrieved 29 November 2021.
10. ^ "Sphere Fluidics and ClexBio giving away CYTRIX hydrogel kits". News-Medical.net. 12 November 2021. Retrieved 29 November 2021.
11. ^ "Sphere Fluidics Wins Award for Academic Spin-Outs Labmate Online". www.labmate-online.com. Retrieved 11 December 2017.
12. ^ "Sphere Fluidics named one of Britain's most disruptive businesses - Cambridge Enterprise". Cambridge Enterprise. Retrieved 11 December 2017.
13. ^ "Future 50 retrospective: Innovating big for the future". Real Business. 28 February 2017. Retrieved 11 December 2017.
14. ^ "Frost & Sullivan Commends Sphere Fluidics for Its Innovative Single-cell Analysis Platform Solution".
15. ^ "Sphere Fluidics receives Queen's Award for Enterprise". News-Medical.net. 21 April 2020. Retrieved 29 November 2021.

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