Suzana Straus

Canadian chemist

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Suzana K. Straus

Born|

Montreal

Alma mater| McGill University
ETH Zurich
Scientific career
Institutions| University of British Columbia
University of Oxford
University of Pennsylvania
Thesis| Development and application of techniques for improving resolution in solid state NMR of fully labelled biomolecules (1998)
Website| Straus Group

Suzana K. Straus is a Canadian chemist who is a professor at the University of British Columbia. Her research focuses on host defense peptides (HDPs), as well as protein-protein and protein-ligand interactions.

## Early life and education

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Straus is from Montreal.[1] She graduated from McGill University with honours in 1993.[2] She completed her doctoral research at ETH Zurich, where she developed new techniques to improve the resolution of solid-state nuclear magnetic resonance experiments.[3] Her doctoral research was supported by the Natural Sciences and Engineering Research Council (NSERC).[citation needed]

## Research and career

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Straus moved to the United States, where she was awarded an NSERC fellowship to join the University of Pennsylvania as a postdoctoral scholar.[citation needed] She was awarded a Dorothy Hodgkin Fellowship in 2000 and moved to the University of Oxford where she worked on structural studies of membrane proteins.[4] In particular, she worked on solid-state magic-angle nuclear magnetic resonance techniques.[5][6]

In 2002, Straus moved to Vancouver, where she was made a professor of chemistry at the University of British Columbia.[1] Her research considers the identification of proteins in their native environments. She combines several spectroscopic and structural probes, including NMR, circular dichroism and differential scanning calorimetry. Her experimental research is used to determine structure-property relationships in biomolecules.[7][8] She has studied the proteins associated with human herpesvirus 6 and human betaherpesvirus 7, and the interactions of these proteins with other binding partners.[7] Straus has simultaneously looked to establish structure-function relationships in HDPs, as well as ways to deliver them.[7][9]

## Selected publications

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* Suzana Straus; Robert E W Hancock (3 March 2006). "Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides". Biochimica et Biophysica Acta. 1758 (9): 1215–1223\. doi:10.1016/J.BBAMEM.2006.02.009. ISSN 0006-3002. PMID 16615993. Wikidata Q36449574.
* Prashant Kumar; Jayachandran N Kizhakkedathu; Suzana K Straus (19 January 2018). "Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo". Biomolecules. 8 (1). doi:10.3390/BIOM8010004. ISSN 2218-273X. PMC 5871973. PMID 29351202. Wikidata Q47723258.
* César de la Fuente-Núñez; Fany Reffuveille; Evan F Haney; Suzana Straus; Robert E W Hancock (May 2014). "Broad-spectrum anti-biofilm peptide that targets a cellular stress response". PLOS Pathogens. 10 (5): e1004152. doi:10.1371/JOURNAL.PPAT.1004152. ISSN 1553-7366. PMC 4031209. PMID 24852171. Wikidata Q28539079.

## Personal life

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Straus has two children.[1] She has campaigned for the government to improve the provision of French speaking education for Canadian children. She served as President of the Federation of Francophone Parents of British Columbia[10] and is active in the community.

## References

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1. ^ a b c "Suzana Straus, New Representative for Greater Vancouver | Fédération des parents francophones de Colombie-Britannique". www.fpfcb.bc.ca. Retrieved 2021-11-16.
2. ^ "Suzana Straus | UBC Chemistry". www.chem.ubc.ca. Retrieved 2021-11-16.
3. ^ Straus, Suzana Katarina (1998). Development and application of techniques for improving resolution in solid state NMR of fully labelled biomolecules (Thesis). OCLC 613987256.
4. ^ Mason, A. James; Grage, Stephan L.; Straus, Suzana K.; Glaubitz, Clemens; Watts, Anthony (2004-03-01). "Identifying Anisotropic Constraints in Multiply Labeled Bacteriorhodopsin by 15N MAOSS NMR: A General Approach to Structural Studies of Membrane Proteins". Biophysical Journal. 86 (3): 1610–1617\. Bibcode:2004BpJ....86.1610M. doi:10.1016/S0006-3495(04)74228-9. ISSN 0006-3495. PMC 1303995. PMID 14990487.
5. ^ Straus, Suzana K. (2004). "Recent Developments in Solid-State Magic-Angle Spinning, Nuclear Magnetic Resonance of Fully and Significantly Isotopically Labelled Peptides and Proteins". Philosophical Transactions: Biological Sciences. 359 (1446): 997–1008\. doi:10.1098/rstb.2003.1398. ISSN 0962-8436. JSTOR 4142212. PMC 1693383. PMID 15306412.
6. ^ "Canadian NMR Research - University of British Columbia". nmr900.ca. Retrieved 2021-11-16.
7. ^ a b c "Research | Straus Group Website". chem-straus.sites.olt.ubc.ca. Retrieved 2021-11-16.
8. ^ "Suzana K. Straus | BPI". bpi.ubc.ca. Retrieved 2021-11-16.
9. ^ Raheem, Nigare; Straus, Suzana K. (2019). "Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions". Frontiers in Microbiology. 10: 2866. doi:10.3389/fmicb.2019.02866. ISSN 1664-302X. PMC 6927293. PMID 31921046.
10. ^ Vachet, Benjamin (October 2018). "Les francophones de Colombie-Britannique se tournent vers la Cour suprême". onfr.tfo.org (in French). Retrieved 2021-11-16.

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