Synthetic Biology Open Language

Standard for exchange of biological designs

The Synthetic Biology Open Language (SBOL)[1] is a proposed data standard for exchanging synthetic biology designs between software packages.[2] It has been under development by the SBOL Developers Group[3] since 2008. This group aims to develop the standard in a way that is open and democratic in order to include as many interests as possible and to avoid domination by a single company. The group also aims to develop and improve the design standard over time as the field of synthetic biology reflects this development.

A graphical modeling language called SBOL Visual has also been created to visualize SBOL designs.[4]

Synthetic Biology Open Language (SBOL) standard visual symbols: promoter, primer binding site, cds, restriction site, etc.

## Releases

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Version  | Date

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1.0 | November 2011
1.1 | October 2012
2.0 | July 2015
2.1.0 | October 2016[5]
3.0  | September 2020

## References

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1. ^ "The Synthetic Biology Open Language (SBOL)".
2. ^ Galdzicki, Michal; Clancy, Kevin P; Oberortner, Ernst; Pocock, Matthew; Quinn, Jacqueline Y; Rodriguez, Cesar A; Roehner, Nicholas; Wilson, Mandy L; Adam, Laura; Anderson, J Christopher; Bartley, Bryan A; Beal, Jacob; Chandran, Deepak; Chen, Joanna; Densmore, Douglas; Endy, Drew; Grünberg, Raik; Hallinan, Jennifer; Hillson, Nathan J; Johnson, Jeffrey D; Kuchinsky, Allan; Lux, Matthew; Misirli, Goksel; Peccoud, Jean; Plahar, Hector A; Sirin, Evren; Stan, Guy-Bart; Villalobos, Alan; Wipat, Anil; Gennari, John H; Myers, Chris J; Sauro, Herbert M (6 June 2014). "The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology". Nature Biotechnology. 32 (6): 545–550\. doi:10.1038/nbt.2891. PMID 24911500.
3. ^ "Governance | the Synthetic Biology Open Language (SBOL)". sbolstandard.org. Archived from the original on 2015-12-01.
4. ^ Quinn, Jacqueline Y.; Cox, Robert Sidney; Adler, Aaron; Beal, Jacob; Bhatia, Swapnil; Cai, Yizhi; Chen, Joanna; Clancy, Kevin; Galdzicki, Michal; Hillson, Nathan J.; Le Novère, Nicolas; Maheshwari, Akshay J.; McLaughlin, James Alastair; Myers, Chris J.; P, Umesh; Pocock, Matthew; Rodriguez, Cesar; Soldatova, Larisa; Stan, Guy-Bart V.; Swainston, Neil; Wipat, Anil; Sauro, Herbert M. (3 December 2015). "SBOL Visual: A Graphical Language for Genetic Designs". PLOS Biology. 13 (12): e1002310. doi:10.1371/journal.pbio.1002310. PMC 4669170. PMID 26633141.
5. ^ Beal, Jacob; Cox, Robert Sidney; Grünberg, Raik; McLaughlin, James; Nguyen, Tramy; Bartley, Bryan; Bissell, Michael; Choi, Kiri; Clancy, Kevin; MacKlin, Chris; Madsen, Curtis; Misirli, Goksel; Oberortner, Ernst; Pocock, Matthew; Roehner, Nicholas; Samineni, Meher; Zhang, Michael; Zhang, Zhen; Zundel, Zach; Gennari, John H.; Myers, Chris; Sauro, Herbert; Wipat, Anil (2016). "Synthetic Biology Open Language (SBOL) Version 2.1.0". Journal of Integrative Bioinformatics. 13 (3): 291. doi:10.1515/jib-2016-291. hdl:1983/5e0058e9-0cfa-40a5-b0b8-6195f61ff524. PMID 28187407.

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