TRAPPC4

Protein-coding gene in the species Homo sapiens

TRAPPC4

| Available structures

PDB| Ortholog search: PDBe RCSB
| List of PDB id codes

2J3T, 2JSN, 2ZMV

Identifiers
Aliases| TRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA, trafficking protein particle complex subunit 4
External IDs| OMIM: 610971; MGI: 1926211; HomoloGene: 105453; GeneCards: TRAPPC4; OMA:TRAPPC4 - orthologs
| Gene location (Human)

Chr.| Chromosome 11 (human)[1]

Band| 11q23.3| Start| 119,018,763 bp[1]
End| 119,025,454 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 9 (mouse)[2]

Band| 9|9 A5.2| Start| 44,314,995 bp[2]
End| 44,318,897 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* islet of Langerhans

* anterior pituitary

* right testis

* left testis

* stromal cell of endometrium

* ganglionic eminence

* right adrenal gland

* left adrenal gland

* left adrenal cortex

* human kidney

| Top expressed in

* medial ganglionic eminence

* right kidney

* ventricular zone

* neural tube

* morula

* otic placode

* granulocyte

* facial motor nucleus

* dentate gyrus of hippocampal formation granule cell

* embryo

More reference expression data
BioGPS| |

More reference expression data
| Gene ontology

Molecular function|

* protein binding

Cellular component|

* cytosol
* Golgi apparatus
* synaptic vesicle
* synapse
* dendrite
* endoplasmic reticulum
* Golgi stack
* Golgi membrane
* TRAPP complex

Biological process|

* dendrite development
* COPII vesicle coating
* vesicle-mediated transport
* endoplasmic reticulum to Golgi vesicle-mediated transport

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

51399

60409

Ensembl| |

ENSG00000280495
ENSG00000196655

ENSMUSG00000032112

UniProt| |

Q9Y296

Q9ES56

RefSeq (mRNA)| | NM_016146
NM_001318486
NM_001318488
NM_001318489
NM_001318490

NM_001318492
NM_001318494

NM_021789

RefSeq (protein)| | NP_001305415
NP_001305417
NP_001305418
NP_001305419
NP_001305421

NP_001305423
NP_057230

NP_068561

Location (UCSC)| Chr 11: 119.02 – 119.03 Mb| Chr 9: 44.31 – 44.32 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Trafficking protein particle complex subunit 4 is a protein that in humans is encoded by the TRAPPC4 gene.[5][6]

## References

[edit]

1. ^ a b c ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 - Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032112 - Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. ^ "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".

## Further reading

[edit]

* Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
* Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
* Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
* Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
* Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
* Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
* Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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PDB gallery

* 2j3t: THE CRYSTAL STRUCTURE OF THE BET3-TRS33-BET5-TRS23 COMPLEX.

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