thioether S-methyltransferase

Identifiers
EC no.| 2.1.1.96
CAS no.| 114797-02-3
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
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PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, a thioether S-methyltransferase (EC 2.1.1.96) is an enzyme that catalyzes the chemical reaction.

S-adenosyl-L-methionine + dimethyl sulfide  ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + trimethylsulfonium

Thus, the two substrates of this enzyme are S-adenosyl methionine and dimethyl sulfide, whereas its two products are S-adenosylhomocysteine and trimethylsulfonium.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase. Other names in common use include S-adenosyl-L-methionine:thioether S-methyltransferase, and thioether methyltransferase.

## References

[edit]

* Mozier NM, McConnell KP, Hoffman JL (1988). "S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism". J. Biol. Chem. 263 (10): 4527–31. PMID 3350800.

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Transferase: one carbon transferases (EC 2.1)

2.1.1: Methyl-|

| N-|

* Histamine N-methyltransferase
* Phenylethanolamine N-methyltransferase
* Amine N-methyltransferase
* Phosphatidylethanolamine N-methyltransferase

|

O-|

* 5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase
* Catechol-O-methyl transferase

Homocysteine|

* Betaine-homocysteine methyltransferase
* Homocysteine methyltransferase
* Methionine synthase

Other|

* Phosphatidyl ethanolamine methyltransferase
* DNMT3B
* Histone methyltransferase
* Thymidylate synthase
* DNA methyltransferase
* Thiopurine methyltransferase
* Cyclopropane-fatty-acyl-phospholipid synthase

2.1.2: Hydroxymethyl-,
Formyl\- and Related|

| Hydroxymethyltransferase|

* Serine hydroxymethyltransferase
* 3-methyl-2-oxobutanoate hydroxymethyltransferase

|

Formyltransferase|

* Phosphoribosylglycinamide formyltransferase
* Inosine monophosphate synthase

Other|

* Glutamate formimidoyltransferase
* Aminomethyltransferase

2.1.3: Carboxy-
and Carbamoyl|

| Carboxy|

* methylmalonyl-CoA carboxytransferase

|

Carbamoyl|

* Aspartate carbamoyltransferase
* Ornithine carbamoyltransferase
* Oxamate carbamoyltransferase
* Putrescine carbamoyltransferase
* 3-hydroxymethylcephem carbamoyltransferase
* Lysine carbamoyltransferase
* N-acetylornithine carbamoyltransferase

2.1.4: Amidine|

* Arginine:glycine amidinotransferase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

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* Biology

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