Transmembrane protein 57

Protein-coding gene in the species Homo sapiens

MACO1

Identifiers
Aliases| MACO1, MACOILIN, transmembrane protein 57, macoilin 1, TMEM57
External IDs| OMIM: 610301; MGI: 1913396; HomoloGene: 14449; GeneCards: MACO1; OMA:MACO1 - orthologs
| Gene location (Human)

Chr.| Chromosome 1 (human)[1]

Band| 1p36.11|1p36.11| Start| 25,430,858 bp[1]
End| 25,500,209 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 4 (mouse)[2]

Band| 4 D3|4 67.11 cM| Start| 134,530,070 bp[2]
End| 134,580,656 bp[2]
| RNA expression pattern

Bgee| | Human| Mouse (ortholog)

|

| Top expressed in

* tendon of biceps brachii

* ganglionic eminence

* buccal mucosa cell

* Skeletal muscle tissue of biceps brachii

* body of pancreas

* gastrocnemius muscle

* islet of Langerhans

* muscle of thigh

* Achilles tendon

* liver

| Top expressed in

* superior cervical ganglion

* Rostral migratory stream

* hand

* Gonadal ridge

* spermatocyte

* zygote

* ganglionic eminence

* otolith organ

* lacrimal gland

* utricle

More reference expression data
BioGPS| | n/a

| Gene ontology

Molecular function|

* molecular function
* microtubule binding
* actin filament binding

Cellular component|

* integral component of membrane
* neuron projection
* axon
* cell projection
* synapse
* nuclear membrane
* neuron projection terminus
* membrane
* nucleus
* endoplasmic reticulum
* rough endoplasmic reticulum membrane

Biological process|

* brain development
* neuronal signal transduction
* chemotaxis

Sources:Amigo / QuickGO
| Orthologs

Species| Human| Mouse
Entrez| |

55219

66146

Ensembl| |

ENSG00000204178

ENSMUSG00000028826

UniProt| |

Q8N5G2

Q7TQE6

RefSeq (mRNA)| |

NM_001282564
NM_018202

NM_025382
NM_001355499
NM_001355500
NM_001355501

RefSeq (protein)| |

NP_001269493
NP_060672

NP_079658
NP_001342428
NP_001342429
NP_001342430

Location (UCSC)| Chr 1: 25.43 – 25.5 Mb| Chr 4: 134.53 – 134.58 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Transmembrane protein 57 is a protein that in humans is encoded by the TMEM57 gene. [5]

## See also

[edit]

* Endoplasmic reticulum protein 57 (Erp57)
* Vicinal (chemistry)

## References

[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000204178 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028826 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: Transmembrane protein 57". Retrieved 2017-10-09.

## Further reading

[edit]

* Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L (2009). "Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts". Nat. Genet. 41 (1): 47–55\. doi:10.1038/ng.269. PMC 2687074. PMID 19060911.
* Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42\. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

|

* v
* t
* e

*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template