Viral cardiomyopathy

Medical condition

Viral cardiomyopathy

Specialty| Cardiology
Symptoms|

* thickening of the myocardium
* dilation of the ventricles

Causes| viral infections cause myocarditis
Diagnostic method| Electrocardiography, Echocardiography, MRI[1]

Viral cardiomyopathy occurs when viral infections cause myocarditis with a resulting thickening of the myocardium and dilation of the ventricles. These viruses include Coxsackie B and adenovirus, echoviruses, influenza H1N1, Epstein–Barr virus, rubella (German measles virus), varicella (chickenpox virus), mumps, measles, parvoviruses, yellow fever, dengue fever, polio, rabies, and the viruses that cause hepatitis A and C,[2][3][4] as well as COVID-19,[5][6] which has been seen to cause this in persons otherwise thought to have a "low risk" of the virus's effects.[7]

## COVID-19 Cardiomyopathy

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Patients with COVID-19 frequently experience heart issues.[8] According to studies, people who have had previous cardiovascular conditions like cardiomyopathy, hypertension, coronary heart disease, or arrhythmia are more likely to become critically ill from SARS-CoV-2 infection. Myocarditis may result from a direct viral infection of the myocardium.[8] Cardiovascular biomarkers like troponin, lactate dehydrogenase, high sensitivity amino-terminal B-type natriuretic peptide, creatinine kinase, and creatinine kinase myocardial band, which indicate myocardial damage, increase in concentration in response to COVID-19.[8] Hundreds of studies have reported myocarditis/myopericarditis caused by COVID-19 infection in living patients, with a male predominance (58%), and a median age of 50 years. [8]

## See also

[edit]

* Coxsackievirus-induced cardiomyopathy
* Myocarditis
* Pericarditis
* Vaccine adverse event

## References

[edit]

1. ^ Schultz, Jason C.; Hilliard, Anthony A.; Cooper, Leslie T.; Rihal, Charanjit S. (1985-01-01). "Diagnosis and Treatment of Viral Myocarditis". Mayo Clinic Proceedings. 84 (11): 1001–1009. doi:10.1016/S0025-6196(11)60670-8. PMC 2770911. PMID 19880690.
2. ^ Barbandi M, Cordero-Reyes A, Orrego CM, Torre-Amione G, Seethamraju H (Jan 2012). "A case series of reversible acute cardiomyopathy associated with H1N1 influenza infection". Methodist DeBakey Cardiovascular Journal. 8 (1): 42–5. doi:10.14797/mdcj-8-1-42. PMC 3405785. PMID 22891110.
3. ^ Badorff C; Lee G. H.; Knowlton K. U. (2000). "Enteroviral cardiomyopathy: bad news for the dystrophin-glycoprotein complex". Herz. 25 (3): 227–32. doi:10.1007/s000590050011. PMID 10904843. S2CID 25973717.
4. ^ Mutlu H, Alam M, Ozbilgin OF (2011). "A rare case of Epstein-Barr virus-induced dilated cardiomyopathy". Heart & Lung. 40 (1): 81–7. doi:10.1016/j.hrtlng.2009.12.012. PMID 20561866.
5. ^ Rathore, Sawai Singh; Rojas, Gianpier Alonzo; Sondhi, Manush; Pothuru, Suveenkrishna; Pydi, Reshma; Kancherla, Neeraj; Singh, Romil; Ahmed, Noman Khurshid; Shah, Jill; Tousif, Sohaib; Baloch, Unaiza Tariq (2021). "Myocarditis associated with Covid-19 disease: A systematic review of published case reports and case series". International Journal of Clinical Practice. 75 (11): e14470. doi:10.1111/ijcp.14470. ISSN 1742-1241. PMID 34235815. S2CID 235768792.
6. ^ Siripanthong, Bhurint; Nazarian, Saman; Muser, Daniele; Deo, Rajat; Santangeli, Pasquale; Khanji, Mohammed Y.; Cooper, Leslie T.; Chahal, C. Anwar A. (September 2020). "Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management". Heart Rhythm. 17 (9): 1463–1471. doi:10.1016/j.hrthm.2020.05.001. ISSN 1547-5271. PMC 7199677. PMID 32387246.
7. ^ Siripanthong B, Nazarian S, Muser D, Deo R, Santangeli P, Khanji M, Cooper L, Jr, Chahal A (5 May 2020). "Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management". Heart Rhythm. 17 (9): 1463–1471. doi:10.1016/j.hrthm.2020.05.001. PMC 7199677. PMID 32387246.
8. ^ a b c d Razaghi, Ali; Szakos, Attila; Al-Shakarji, Riham; Björnstedt, Mikael; Szekely, Laszlo (2022-12-31). "Morphological changes without histological myocarditis in hearts of COVID-19 deceased patients". Scandinavian Cardiovascular Journal. 56 (1): 166–173. doi:10.1080/14017431.2022.2085320. ISSN 1401-7431. PMID 35678649. S2CID 249521076.

## External links

[edit]

* Myocarditis on emedicine

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Cardiovascular disease (heart)

Ischemia|

| Coronary disease|

* Coronary artery disease (CAD)
* Coronary artery aneurysm
* Spontaneous coronary artery dissection (SCAD)
* Coronary thrombosis
* Coronary vasospasm
* Myocardial bridge

|

Active ischemia|

* Angina pectoris
* Prinzmetal's angina
* Stable angina
* Acute coronary syndrome
* Myocardial infarction
* Unstable angina

Sequelae|

* hours
* Hibernating myocardium
* Myocardial stunning
* days
* Myocardial rupture
* weeks
* Ventricular aneurysm
* Dressler syndrome

Layers|

| Pericardium|

* Pericarditis
* Acute
* Chronic / Constrictive
* Pericardial effusion
* Cardiac tamponade
* Hemopericardium

|

Myocardium|

* Myocarditis
* Chagas disease
* Cardiomyopathy
* Dilated
* Alcoholic
* Hypertrophic
* Tachycardia-induced
* Restrictive
* Loeffler endocarditis
* Cardiac amyloidosis
* Endocardial fibroelastosis
* Viral
* Arrhythmogenic right ventricular dysplasia

Endocardium /
valves|

| Endocarditis|

* infective endocarditis
* Subacute bacterial endocarditis
* non-infective endocarditis
* Libman–Sacks endocarditis
* Nonbacterial thrombotic endocarditis

|

Valves|

* mitral
* prolapse
* stenosis
* regurgitation
* aortic
* stenosis
* regurgitation
* tricuspid
* stenosis
* regurgitation
* pulmonary
* stenosis
* regurgitation

Conduction /
arrhythmia|

| Bradycardia|

* Sinus bradycardia
* Sick sinus syndrome
* Heart block: Sinoatrial
* AV
* 1°
* 2°
* 3°
* Intraventricular
* Bundle branch block
* Right
* Left
* Left anterior fascicle
* Left posterior fascicle
* Bifascicular
* Trifascicular
* Adams–Stokes syndrome

|

Tachycardia
(paroxysmal and sinus)|

| Supraventricular|

* Atrial
* Multifocal
* Junctional
* AV nodal reentrant
* Junctional ectopic

|

Ventricular|

* Accelerated idioventricular rhythm
* Catecholaminergic polymorphic
* Torsades de pointes

Premature contraction|

* Atrial
* Junctional
* Ventricular

Pre-excitation syndrome|

* Lown–Ganong–Levine
* Wolff–Parkinson–White

Flutter / fibrillation|

* Atrial flutter
* Ventricular flutter
* Atrial fibrillation
* Familial
* Ventricular fibrillation

Pacemaker|

* Ectopic pacemaker / Ectopic beat
* Multifocal atrial tachycardia
* Pacemaker syndrome
* Parasystole
* Wandering atrial pacemaker

Long QT syndrome|

* Andersen–Tawil
* Jervell and Lange-Nielsen
* Romano–Ward

Cardiac arrest|

* Sudden cardiac death
* Asystole
* Pulseless electrical activity
* Sinoatrial arrest

Other / ungrouped|

* hexaxial reference system
* Right axis deviation
* Left axis deviation
* QT
* Short QT syndrome
* T
* T wave alternans
* ST
* J wave
* ST elevation
* ST depression
* Strain pattern

Cardiomegaly|

* Ventricular hypertrophy
* Left
* Right
* Pulmonary
* Atrial enlargement
* Left
* Right
* Athletic heart syndrome

Other|

* Cardiac fibrosis
* Heart failure
* Diastolic heart failure
* Cardiac asthma
* Rheumatic fever
* Obstructive shock

* v
* t
* e

Inflammation

Symptoms|

* Flushing (Rubor)
* Fever (Calor)
* Swelling (Tumor)
* Pain (Dolor)
* Loss of function (Functio laesa)

Mechanism|

| Acute|

| Plasma-derived mediators|

* Bradykinin
* complement
* C3
* C5a
* MAC
* coagulation
* Factor XII
* Plasmin
* Thrombin

|

Cell-derived mediators|

| preformed|

* Lysosome granules
* biogenic amines
* Histamine
* Serotonin

|

synthesized on demand|

* cytokines
* IFN-γ
* IL-8
* TNF-α
* IL-1
* eicosanoids
* Leukotriene B4
* Prostaglandins
* Nitric oxide
* Kinins

Chronic|

* Macrophage
* Epithelioid cell
* Giant cell
* Granuloma

Other|

* Acute-phase reaction
* Vasodilation
* Increased vascular permeability
* Exudate
* Leukocyte extravasation
* Chemotaxis

Tests|

* Full blood count
* Leukocytosis
* C-reactive protein
* Erythrocyte sedimentation rate

General|

* Lymphadenopathy
* List of inflammatory disorders

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