Drug discovery

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This page lists current researches in developing new medications.

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# Anxiolytic and Sleep Inducers

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* Isovitexin and 6-C-glycoside-Diosmetin - They produce anxiolytic-like and cognitive-enhancing effects.[1]
* Cannabidiol[2]

# Antidepressants

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* Cannabidiol[2]

# Cancer Therapy

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# Immunology

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* Dopaminergic System in Autoimmunity[3], Bupropion[4][5][6]
* Cannabidiol - Inhibits TNF-α[7]

# Reduction of nicotine addiction

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* Cannabidiol[8]

# See Also

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* Medical Research

# References

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1. ↑ Oliveira, Daniela Rodrigues de; Todo, Andréia Hatsue; Rêgo, Gizelda Maia; Cerutti, Janete Maria; Cavalheiro, Alberto José; Rando, Daniela Gonçales Galasse; Cerutti, Suzete Maria (July 2018). "Flavones-bound in benzodiazepine site on GABA A receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin". European Journal of Pharmacology (Elsevier) 831: 77–86. doi:10.1016/j.ejphar.2018.05.004. ISSN 0014-2999. PMID 29738701.
2. ↑ 2.0 2.1 de Mello Schier, Alexandre R.; de Oliveira Ribeiro, Natalia P.; Coutinho, Danielle S.; Machado, Sergio; Arias-Carrión, Oscar; Crippa, Jose A.; Zuardi, Antonio W.; Nardi, Antonio E. et al. (2014). "Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa". CNS & neurological disorders drug targets 13 (6): 953–960. doi:10.2174/1871527313666140612114838. ISSN 1996-3181. PMID 24923339. https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/11/2014-Antidepressant-Like-and-Anxiolytic-Like-Effects-of-Cannabidiol.pdf.
3. ↑ Vidal, PM; Pacheco, R (2019-01-19). "Targeting the Dopaminergic System in Autoimmunity". Journal of Neuroimmune Pharmacology (Springer). doi:10.1007/s11481-019-09834-5. ISSN 1557-1890. PMID 30661214. http://link.springer.com/10.1007/s11481-019-09834-5.
4. ↑ Kast, RE; Altschuler, EL (Nov 2001). "Remission of Crohn's disease on bupropion". Gastroenterology (Elsevier) 121 (5): 1260–1261. doi:10.1053/gast.2001.29467. ISSN 0016-5085. PMID 11706830. https://linkinghub.elsevier.com/retrieve/pii/S0016508501700212.
5. ↑ Mosaic, LS. "Why a third of antidepressants are prescribed for something else". CNN. Retrieved 2019-07-06.
6. ↑ Brustolim, D; Ribeiro-dos-Santos, R; Kast, RE; Altschuler, EL; Soares, MBP (Jun 2006). "A new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice". International Immunopharmacology (Elsevier) 6 (6): 903–907. doi:10.1016/j.intimp.2005.12.007. ISSN 1567-5769. PMID 16644475. https://linkinghub.elsevier.com/retrieve/pii/S1567576906000026.
7. ↑ Mechoulam, Raphael; Peters, Maximilian; Murillo-Rodriguez, Eric; Hanus, Lumír O. (Aug 2007). "Cannabidiol--recent advances". Chemistry & Biodiversity 4 (8): 1678–1692. doi:10.1002/cbdv.200790147. ISSN 1612-1880. PMID 17712814. https://www.researchgate.net/profile/Eric_Murillo-Rodriguez/publication/6126753_Cannabidiol_-_Recent_Advances/links/5a1f215ea6fdccc6b7fb18d7/Cannabidiol-Recent-Advances.pdf.
8. ↑ Morgan, Celia J. A.; Das, Ravi K.; Joye, Alyssa; Curran, H. Valerie; Kamboj, Sunjeev K.; Mechoulam, Raphael; Weller, Aron (2013-9). "Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings". Addictive Behaviors 38 (9): 2433–2436. doi:10.1016/j.addbeh.2013.03.011. ISSN 1873-6327. PMID 23685330. https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/11/CBDcigarettes.pdf.