Interleukin-2

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Interleukin-2 is an interleukin generated by T4 helper lymphocytes. It induces DNA synthesis in naive lymphocytes. Other terms include Lymphocyte Mitogenic Factor, T-Cell Growth Factor, Thymocyte Stimulating Factor and T-Cell Stimulating Factor.^[1]

The gene expresses when stimulated by human T-cell leukemia virus Type 1.^[2]

Thalidomide has a costimulatory or adjuvant effect on T-lymphocytes resulting in increased T-cell proliferation and increased production of interleukin-2 and interferon gamma.^[3]

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