From Citizendium - Reading time: 1 min
In medicine, a thyroid nodule is a "small circumscribed mass in the thyroid gland that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (goiter, nodular)."[1] About 5% of thyroid nodules, including incidentalomas, contain thyroid cancer.[2]
A decision analysis of conflicting clinical practice guidelines concluded that selected biopsy of nodules 10-14 mm in size is better than routine biopsies.[3]