Acylpyruvate hydrolase
Topic: Biology
From HandWiki - Reading time: 1 min
Short description: Class of enzymes
| acylpyruvate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.7.1.5 | ||||||||
| CAS number | 54004-67-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an acylpyruvate hydrolase (EC 3.7.1.5) is an enzyme that catalyzes the chemical reaction
- a 3-acylpyruvate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] a carboxylate + pyruvate
Thus, the two substrates of this enzyme are 3-acylpyruvate and water, whereas its two products are carboxylate and pyruvate.
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 3-acylpyruvate acylhydrolase. This enzyme participates in tyrosine metabolism.
References
- "Microbial metabolism of the pyridine ring. The metabolism of pyridine-3,4-diol (3,4-dihydroxypyridine) by Agrobacterium sp". Biochem. J. 140 (2): 277–92. 1974. PMID 4375963.
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