From HandWiki - Reading time: 3 min
| mir-589 | |
|---|---|
| Identifiers | |
| Symbol | mir-589 |
| Rfam | RF00987 |
| miRBase family | MIPF0000496 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-589 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
miR-589 has been implicated in the regulation of antimicrobial targets in bovine lung alveolar macrophages, and alongside other miRNAs has been suggested to play a part in the immune response against Mycobacterium tuberculosis.[1] It has additionally been linked to HLA-G expression, having been found to target the 3'UTR 14-base pair sequence region of the HLA-G gene.[2]