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Streptothricin hydrolase

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Streptothricin hydrolase
Identifiers
EC number3.5.2.19
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Streptothricin hydrolase (EC 3.5.2.19, sttH (gene)) is an enzyme with systematic name streptothricin-F hydrolase.[1][2] This enzyme catalyses the following chemical reaction

streptothricin-F + H2O [math]\displaystyle{ \rightleftharpoons }[/math] streptothricin-F acid

The enzyme also catalyses the hydrolysis of streptothricin-D to streptothricin-D acid.

References

  1. "The biological function of the bacterial isochorismatase-like hydrolase SttH". Bioscience, Biotechnology, and Biochemistry 73 (11): 2494–500. November 2009. doi:10.1271/bbb.90499. PMID 19897889. 
  2. "A novel enzyme conferring streptothricin resistance alters the toxicity of streptothricin D from broad-spectrum to bacteria-specific". The Journal of Biological Chemistry 281 (25): 16842–8. June 2006. doi:10.1074/jbc.m602294200. PMID 16641084. 

External links




Licensed under CC BY-SA 3.0 | Source: https://handwiki.org/wiki/Biology:Streptothricin_hydrolase
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