2-(Ethylamino)-1,2-diphenylethanone

2-(Ethylamino)-1,2-diphenylethanone
Clinical data
ATC code	None;
Identifiers
	IUPAC name 2-(ethylamino)-1,2-diphenylethanone;
CAS Number	22312-16-9 ;
PubChem CID	69702363;
UNII	8R3EAH84GZ;
Chemical and physical data
Formula	C16H17NO
Molar mass	239.318 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2;
	InChI InChI=1S/C16H17NO/c1-2-17-15(13-9-5-3-6-10-13)16(18)14-11-7-4-8-12-14/h3-12,15,17H,2H2,1H3; Key:NHNVMSYWZNJBOO-UHFFFAOYSA-N;

Short description: Chemical compound

2-(Ethylamino)-1,2-diphenylethanone (also known as α-ethylamino-deoxybenzoin, [α-(Ethylamino)benzyl]-(phenyl)-ketone and βk-Ephenidine) is a chemical compound which was first invented in 1955,^[1] researched by ICI in 1969 as an antidepressant,^[2] and subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1.^[3] No other pharmacological data has been disclosed, though its chemical structure closely resembles that of certain designer drug compounds such as ephenidine and N-ethylhexedrone.

References

↑ "Über α-Alkylamino-ketone.". Helvetica Chimica Acta 38 (6): 1415–1420. 1955. doi:10.1002/hlca.19550380613.
↑ Gilman DJ, "Desyl amines and compositions thereof. gdate = 19 February 1969", GB patent 1143263, assigned to ICI Ltd.
↑ Barton P, Clarke D, Davies C, Hargreaves R, Pease J, Rankine M, "Ketones", US patent Abandoned 2005272036, published 8 December 2005, assigned to AstraZeneca AB

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[1] "Über α-Alkylamino-ketone.". Helvetica Chimica Acta 38 (6): 1415–1420. 1955. doi:10.1002/hlca.19550380613.

[2] Gilman DJ, "Desyl amines and compositions thereof. gdate = 19 February 1969", GB patent 1143263, assigned to ICI Ltd.

[3] Barton P, Clarke D, Davies C, Hargreaves R, Pease J, Rankine M, "Ketones", US patent Abandoned 2005272036, published 8 December 2005, assigned to AstraZeneca AB

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[2]

[3]

2-(Ethylamino)-1,2-diphenylethanone

Topic: Chemistry

See also

References

Clinical data

ATC code	None
Identifiers
IUPAC name 2-(ethylamino)-1,2-diphenylethanone
CAS Number	22312-16-9^Y
PubChem CID	69702363
UNII	8R3EAH84GZ
Chemical and physical data
Formula	C₁₆H₁₇NO
Molar mass	239.318 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCNC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2
InChI InChI=1S/C16H17NO/c1-2-17-15(13-9-5-3-6-10-13)16(18)14-11-7-4-8-12-14/h3-12,15,17H,2H2,1H3 Key:NHNVMSYWZNJBOO-UHFFFAOYSA-N