Alanosine

Alanosine
Clinical data
ATC code	None;
Identifiers
	IUPAC name (S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid;
CAS Number	5854-93-3 ;
PubChem CID	22128;
ChemSpider	20787 ;
UNII	2CNI71214Y;
ChEMBL	ChEMBL452715 ;
Chemical and physical data
Formula	C3H7N3O4
Molar mass	149.106 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)[C@@H](N)CN(O)N=O;
	InChI InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1 ; Key:MLFKVJCWGUZWNV-REOHCLBHSA-N ;
	(verify)

Short description: Chemical compound

Alanosine (also called SDX-102)^[1] is a substance that has been studied for the treatment of pancreatic cancer.^[2] It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.^{[needs update]}

References

↑ PubChem. "Alanosine" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/135409347.
↑ "Alanosine (UCSD)". Current Opinion in Investigational Drugs 2 (11): 1623–30. November 2001. PMID 11763167.

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Original source: https://en.wikipedia.org/wiki/Alanosine. Read more

[1] PubChem. "Alanosine" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/135409347.

[2] "Alanosine (UCSD)". Current Opinion in Investigational Drugs 2 (11): 1623–30. November 2001. PMID 11763167.

[1]

[2]

Clinical data


ATC code	None
Identifiers
IUPAC name (S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid
CAS Number	5854-93-3^Y
PubChem CID	22128
ChemSpider	20787^Y
UNII	2CNI71214Y
ChEMBL	ChEMBL452715^Y
Chemical and physical data
Formula	C₃H₇N₃O₄
Molar mass	149.106 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(O)[C@@H](N)CN(O)N=O
InChI InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1^Y Key:MLFKVJCWGUZWNV-REOHCLBHSA-N^Y
(verify)

Alanosine

Topic: Chemistry

References