Benpyrine

Benpyrine is an experimental drug which binds to TNF-α and blocks TNF-α mediated signaling. It has antiinflammatory effects and is used in pharmacological research into various inflammatory processes mediated via TNF-α.^[1]^[2]

References

↑ "Discovery of an Orally Active Small-Molecule Tumor Necrosis Factor-α Inhibitor". Journal of Medicinal Chemistry 63 (15): 8146–8156. August 2020. doi:10.1021/acs.jmedchem.0c00377. PMID 32667202.
↑ "Structure-Based Drug Design and Synthesis of Pyrrolidine-2,5-diones as Novel TNF-α Inhibitors". Journal of Chemical Information and Modeling 63 (12): 3911–3924. June 2023. doi:10.1021/acs.jcim.2c01458. PMID 37284855.

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[1] "Discovery of an Orally Active Small-Molecule Tumor Necrosis Factor-α Inhibitor". Journal of Medicinal Chemistry 63 (15): 8146–8156. August 2020. doi:10.1021/acs.jmedchem.0c00377. PMID 32667202.

[2] "Structure-Based Drug Design and Synthesis of Pyrrolidine-2,5-diones as Novel TNF-α Inhibitors". Journal of Chemical Information and Modeling 63 (12): 3911–3924. June 2023. doi:10.1021/acs.jcim.2c01458. PMID 37284855.

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Benpyrine

Topic: Chemistry

See also

References