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Linuron
Topic: Chemistry
From HandWiki - Reading time: 5 min
Linuron is a phenylurea herbicide[1] that is used to control the growth of grass and weeds for the purpose of supporting the growth of crops like soybeans.[2][3] It is registered for use in India.[4]
Pharmacology
Mechanism of action
Effects in animals
Linuron has been found to produce reproductive toxicity in animals by acting as an androgen receptor (AR) antagonist, and for this reason, is considered to be an endocrine disruptor.[2][5] Consequently, in January 2017, the Standing Committee on Plants, Animals, Food and Feed (SCoPAFF) of the European Commission DG "Health and food safety" decided to not renew its regulatory approval.[6] Sales are expected to cease by June 2017.[6]
See also
- Diuron
- Monolinuron
References
- ↑ "Linuron and monolinuron". Residue Reviews. Reviews of Environmental Contamination and Toxicology. 77. 1981. pp. 1–364. doi:10.1007/978-1-4612-5874-2_1. ISBN 978-1-4612-5876-6.
- ↑ 2.0 2.1 Understanding Toxicology. Jones & Bartlett Learning. 30 August 2016. pp. 705–. ISBN 978-1-284-12761-4. https://books.google.com/books?id=OQ0hDQAAQBAJ&pg=PA705.
- ↑ Metabolic Pathways of Agrochemicals. Royal Society of Chemistry. 1998. pp. 744–. ISBN 978-0-85404-494-8. https://books.google.com/books?id=uC2-Ocob_MMC&pg=PA744.
- ↑ The Pesticide Encyclopedia. CABI. 2015. ISBN 978-1-78064-014-3.
- ↑ European Food Safety Authority (EFSA) (July 2016). "Peer review of the pesticide risk assessment of the active substance linuron". EFSA Journal 14 (7). doi:10.2903/j.efsa.2016.4518.
- ↑ 6.0 6.1 "Linuron fails to gain renewed approval". Briefing Media Ltd. https://www.fginsight.com/news/linuron-fails-to-gain-renewed-approval-17923.
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