MDAT

MDAT
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine;
CAS Number	101625-35-8 ; hydrochloride: 3446-21-8 ;
PubChem CID	36483;
ChemSpider	33531;
UNII	28IR5LC41Q; hydrochloride: BOX4U52EET ;
Chemical and physical data
Formula	C11H13NO2
Molar mass	191.230 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C3Cc1cc2OCOc2cc1CC3N;

Short description: Chemical compound

6,7-Methylenedioxy-2-aminotetralin (MDAT) is a drug developed in the 1990s by a team at Purdue University led by David E. Nichols.^[1] It appears to act as a serotonin releasing agent based on rodent drug discrimination assays comparing it to MDMA, in which it fully substitutes for, and additionally lacks any kind of serotonergic neurotoxicity.^[1] Hence, MDAT is considered likely to be a non-neurotoxic, putative entactogen in humans.

References

↑ ^1.0 ^1.1 "Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry 33 (2): 703–10. February 1990. doi:10.1021/jm00164a037. PMID 1967651.

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[pmid1967651-1] 1.0 ^1.1 "Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry 33 (2): 703–10. February 1990. doi:10.1021/jm00164a037. PMID 1967651.

[1]

v t e Empathogens/entactogens
Phenylalkyl- amines (other than cathinones)	Unfused benzene ring: 3-CMA 4-CAB 4-FA 4-MA 4-MMA 4-FMA 4-MTA 4,4'-DMAR Ariadne Metaescaline MMA PMA PMEA PMMA mMMA Benzodioxine: EDMA Benzodioxoles: Phenethylamine: { Lophophine } Amphetamines: { 2-Methyl-MDA 2,3-MDA 3,4-MDA (tenamfetamine) 5-Methyl-MDA 6-Methyl-MDA DiFMDA DMMDA DMMDA-2 EIDA MDEA MDMA (midomafetamine) MDMOH MDOH MMDA MMDA-2 MMDMA } 1-Phenylbutan-2-amines: { BDB EBDB MBDB } Phentermines: { MDMP MDPH } Benzofurans and dihydrobenzofurans: 5-APB 5-APDB 5-EAPB 5-MAPB 5-MAPDB 5-MBPB 6-APB 6-APDB 6-EAPB 6-MAPB 6-MAPDB IBF5MAP Indanes: 5-APDI 5-MAPDI Indoles: 5-IT 6-API Naphthalenes: Methamnetamine Naphthylaminopropane Tetralin: 6-APT
Cyclized phenyl- alkylamines	Aminoindanes: 5-IAI AMMI ETAI MDAI MDMAI MMAI MEAI NM-2-AI TAI Aminotetralins: 6-CAT MDAT MDMAT
Cathinones	3-MMC 4-EMC Brephedrone Butylone Ethylone Eutylone Flephedrone Mephedrone Methedrone Methylone TH-PVP
Tryptamines	4-Methyl-αET αET αMT
Chemical classes	Substituted amphetamine Sub. benzofuran Sub. cathinone Sub. MDPEA Sub. PEA Sub. tryptamine

MDAT

Topic: Chemistry

See also

References

Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine
CAS Number	101625-35-8^Y hydrochloride: 3446-21-8^Y
PubChem CID	36483
ChemSpider	33531
UNII	28IR5LC41Q hydrochloride: BOX4U52EET^Y
Chemical and physical data
Formula	C₁₁H₁₃NO₂
Molar mass	191.230 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C3Cc1cc2OCOc2cc1CC3N