Narasin

Narasin
Clinical data
Other names	(4S)-4-methyl-salinomycin
AHFS/Drugs.com	International Drug Names
ATCvet code	QP51BB04 (WHO) QP51BB54 (WHO);
Identifiers
	IUPAC name (2R)-2-[(2R,3S,5S,6R)-6-[(1S,2S,3S,5R)-5- [(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]-3,5-dimethyl-2-tetrahydropyranyl]butanoic acid;
CAS Number	55134-13-9 ;
PubChem CID	65452;
ChemSpider	58911;
UNII	DZY9VU539P;
Chemical and physical data
Formula	C43H72O11
Molar mass	765.038 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C(O)=O)([H])[C@@H](C)C[C@@H]5C)[C@H](CC)[C@@]1([H])O[C@@]2(O[C@@]3(CC[C@]([C@]4([H])O[C@@H](C)[C@@](O)(CC)CC4)(C)O3)[C@H](O)C=C2)[C@H](C)C[C@@H]1C;
	InChI InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1; Key:VHKXXVVRRDYCIK-CWCPJSEDSA-N;
	(verify)

Short description: Chemical compound

Narasin is a coccidiostat and antibacterial agent.^[1]^[2] It is a derivative of salinomycin with an additional methyl group. Narasin is produced by fermentation of a strain of Streptomyces aureofaciens.^[3]

References

↑ "The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites". Avian Diseases 55 (1): 59–64. March 2011. doi:10.1637/9572-101310-Reg.1. PMID 21500637.
↑ "Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone". American Journal of Veterinary Research 50 (7): 1056–1059. July 1989. PMID 2774323.
↑ "Veterinary Drugs Residues: Coccidiostats". Encyclopedia of Food Safety. 2014. pp. 63–75. doi:10.1016/B978-0-12-378612-8.00246-8. ISBN 9780123786135.

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[1] "The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites". Avian Diseases 55 (1): 59–64. March 2011. doi:10.1637/9572-101310-Reg.1. PMID 21500637.

[2] "Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone". American Journal of Veterinary Research 50 (7): 1056–1059. July 1989. PMID 2774323.

[3] "Veterinary Drugs Residues: Coccidiostats". Encyclopedia of Food Safety. 2014. pp. 63–75. doi:10.1016/B978-0-12-378612-8.00246-8. ISBN 9780123786135.

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Narasin

Topic: Chemistry

References