Potassium ascorbate

Potassium ascorbate
Names
	Preferred IUPAC name Potassium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
	Other names Monopotassium ascorbate; Potassium L-ascorbate
Identifiers
CAS Number	15421-15-5 ;
3D model (JSmol)	Interactive image;
ChemSpider	30647045;
PubChem CID	23687519;
UNII	X5523762RI ;
	InChI InChI=1S/C6H8O6.K/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1 Key: CONVKSGEGAVTMB-RXSVEWSESA-M;
	SMILES OC1=C([O-])[C@]([C@@H](O)CO)([H])OC1=O.[K+];
Properties
Chemical formula	C6H7KO6
Molar mass	214.214 g·mol−1
Solubility in water	98g/100mL
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Potassium ascorbate is a compound with formula KC₆H₇O₆. It is the potassium salt of ascorbic acid (vitamin C) and a mineral ascorbate. As a food additive, it has E number E303, INS number 303. Although it is not a permitted food additive in the UK, USA and the EU,^[2]^[3] it is approved for use in Australia and New Zealand.^[4] According to some studies, it has shown a strong antioxidant activity and antitumoral properties.^[5]^[6]^[7]

References

↑ Burdoch, George A. (1997). Encyclopedia of food and color additives. Boca Raton, Florida: CRC Press. p. 207. ISBN 0-8493-9412-0. https://books.google.com/books?id=5BZ39iL0XfQC&pg=PA207. Retrieved 2012-09-30.
↑ UK Food Standards Agency: "Current EU approved additives and their E Numbers". http://www.food.gov.uk/safereating/chemsafe/additivesbranch/enumberlist. Retrieved 2011-10-27.
↑ Noshly. "Wise Eating, Made Easy" (in en). http://noshly.com/.
↑ Australia New Zealand Food Standards Code"Standard 1.2.4 - Labelling of ingredients". 8 September 2011. http://www.comlaw.gov.au/Details/F2011C00827. Retrieved 2011-10-27.
↑ Frajese, Giovanni Vanni; Benvenuto, Monica; Fantini, Massimo; Ambrosin, ELENA; Sacchetti, Pamela; Masuelli, Laura; Giganti, Maria Gabriella; Modesti, Andrea et al. (June 2016). "Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro". Oncology Letters 11 (6): 4224–4234. doi:10.3892/ol.2016.4506. ISSN 1792-1074. PMID 27313770.
↑ Cavicchio, Carlotta; Benedusi, Mascia; Pambianchi, Erika; Pecorelli, Alessandra; Cervellati, Franco; Savelli, Vinno; Calamandrei, Duccio; Maellaro, Emilia et al. (2017). "Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment". Oxidative Medicine and Cellular Longevity 2017. doi:10.1155/2017/4256519. ISSN 1942-0900. PMID 29290903.
↑ Anichini, C.; Lotti, F.; Longini, M.; Proietti, F.; Felici, C.; Perrone, S.; Buonocore, G. (2012). "Antioxidant effects of potassium ascorbate with ribose therapy in a case with Prader Willi Syndrome". Disease Markers 33 (4): 179–183. doi:10.3233/DMA-2012-0922. ISSN 1875-8630. PMID 22960339.

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[1] Burdoch, George A. (1997). Encyclopedia of food and color additives. Boca Raton, Florida: CRC Press. p. 207. ISBN 0-8493-9412-0. https://books.google.com/books?id=5BZ39iL0XfQC&pg=PA207. Retrieved 2012-09-30.

[2] UK Food Standards Agency: "Current EU approved additives and their E Numbers". http://www.food.gov.uk/safereating/chemsafe/additivesbranch/enumberlist. Retrieved 2011-10-27.

[3] Noshly. "Wise Eating, Made Easy" (in en). http://noshly.com/.

[4] Australia New Zealand Food Standards Code"Standard 1.2.4 - Labelling of ingredients". 8 September 2011. http://www.comlaw.gov.au/Details/F2011C00827. Retrieved 2011-10-27.

[5] Frajese, Giovanni Vanni; Benvenuto, Monica; Fantini, Massimo; Ambrosin, ELENA; Sacchetti, Pamela; Masuelli, Laura; Giganti, Maria Gabriella; Modesti, Andrea et al. (June 2016). "Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro". Oncology Letters 11 (6): 4224–4234. doi:10.3892/ol.2016.4506. ISSN 1792-1074. PMID 27313770.

[6] Cavicchio, Carlotta; Benedusi, Mascia; Pambianchi, Erika; Pecorelli, Alessandra; Cervellati, Franco; Savelli, Vinno; Calamandrei, Duccio; Maellaro, Emilia et al. (2017). "Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment". Oxidative Medicine and Cellular Longevity 2017. doi:10.1155/2017/4256519. ISSN 1942-0900. PMID 29290903.

[7] Anichini, C.; Lotti, F.; Longini, M.; Proietti, F.; Felici, C.; Perrone, S.; Buonocore, G. (2012). "Antioxidant effects of potassium ascorbate with ribose therapy in a case with Prader Willi Syndrome". Disease Markers 33 (4): 179–183. doi:10.3233/DMA-2012-0922. ISSN 1875-8630. PMID 22960339.

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Potassium ascorbate

Topic: Chemistry

References