Galderma

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Galderma S.A.
TypePublic
SIXGALD
Industry
  • Dermatology
  • Pharmaceuticals
Founded1981; 45 years ago (1981) (as a joint venture between L'Oréal and Nestlé)
HeadquartersZug, Switzerland
Key people
  • Flemming Ørnskov (CEO)
  • Thomas Ebeling (chairman)
RevenueIncrease US$4.41 billion (2024)[1]
Owner
  • Consortium led by EQT AB (2019–2024)
  • Nestle (1981–2019)
  • L'Oréal (1981–2014)
Number of employees
6,500 (2024)[2]
Websitegalderma.com

Galderma S.A. is a Swiss pharmaceutical company based in Zug that specializes in dermatological treatments and skin care products. Formerly a subsidiary of L'Oréal and Nestlé, it was acquired by a consortium of private institutional investors in 2019 and remained under their ownership until its initial public offering in 2024.[3]

Galderma was formed in 1981 as a joint venture between Nestlé and L'Oréal, and later became a wholly owned subsidiary of Nestlé.[4] Since 2019, it has belonged to an investment consortium. The company, headed by president and CEO Flemming Ørnskov (ex-Shire), has 33 sites in 100 countries[5] with a worldwide network of distributors and employs more than 4,600 people.

History

The origins of Galderma date back to 1961 and the founding of the Owen dermatology company in Dallas, Texas, USA by M. Owen.[6]

In 1979, Hans Schaefer founded the International Center for Dermatological Research (CIRD) in Sophia Antipolis, with the support of the CEO of L'Oréal, François Dalle, who wanted to diversify his cosmetic research into the drug sector. At the same time, Nestlé, which also had ambitions in dermatology bought the Owen laboratory.

L'Oréal and Nestlé formed a joint venture in 1981 and created Galderma (CIRD became Galderma R&D).[7][8]

Galderma expanded by specializing in the research, development, and commercialization of products for dermatology (skincare) patients. It reached a significant size, with 38 subsidiaries present in 100 countries in the 2010s.[5] It diversified into aesthetic medicine products with the botulinum toxin Azzalure, a field in which it strengthened in 2010 with the acquisition of the Swedish medical device company Q-Med.[9]

Nestlé bought back all the shares from L'Oréal in 2014, creating a new unit of Nestlé group called Nestlé Skin Health. The transaction had a value of €3.1 billion (US$4.23 billion) and was paid for by Nestlé with 21.2 million L'Oréal shares.[10]

In 2019, Nestlé sold Galderma for $10.2 billion[11][12] to a consortium comprising the EQT VIII fund, Luxinva (a wholly owned subsidiary of Abu Dhabi Investment Authority), PSP Investments and other institutional investors. Since then, it has been the largest independent dermatology company in the world.[13]

Galderma bought California-based Alastin, a firm specializing in specialist skincare products, for an undisclosed price in November 2021.[6][14]

In June 2022, Galderma announced positive results in two Phase III trials for liquid botulinum toxin A, showing RelabotulinumtoxinA was well tolerated.[15] The company also accounted positive data from the Phase III trial, showing the efficacy and safety of Nemolizumab in patients with prurigo nodularis at the 2023 European Academy of Dermatology and Venereology congress in Berlin.[16] Nemolizumab is a monoclonal antibody that blocks the signaling of IL-31, a neuroimmune cytokine involved in the pathogenesis of prurigo Nodularis.[17]

On 6 March 2023, Galderma announced its intention to list on the Swiss stock exchange.[18]

The IPO took place on 22 March 2024 and was one of the biggest in Europe in two years and the largest in Switzerland since 2017.[19][20] The stock price went up to 62,68 Swiss francs, up from the IPO price at 53 francs per share.[21] The company will repay debt with offering proceeds.[21]

Activities

Aesthetics

In 2007, Galderma and Ipsen signed a licensing agreement for the distribution of the botulinum toxin Dysport, known as Azzalure in the European Union. More than 40 million treatments have been performed in the United States and the European Union.[22]

The main brands are Restylane, Azzalure, Dysport, Alluzience, Sculptra and Relfydess (relabotulinumtoxinA), which received a positive decision for use in Australia[23] and in the European Union in July 2024.[24]

Consumer care

Prescription Medicine

The main brands are Aklief, Benzac, Cetaphil, Epiduo, Epiduo Forte, Twyneo, Epsolay, Loceryl, Differin, Soolantra, Mirvaso, Oracea, Metvix and Nemluvio which received US Food and Drug Administration approval for adult patients living with prurigo nodularis in August 2024[25] and for patients with atopic dermatitis in December 2024.[26]

Research and development

The company invests substantially in research and development and sources new treatments from its own activities and from its partnerships with others. It divides its research and development departments between six sites:

  • Lausanne, Switzerland
  • Zug, Switzerland
  • Uppsala, Sweden
  • Dallas, Texas
  • Bridgewater, New Jersey

Production

  • The Alby-sur-Chéran plant in France, inaugurated in 1994, supplies over 70 countries.
  • The Baie d'Urfé (Montreal) facility in Canada started production in 2000 and supplies Cetaphil globally.
  • The plant in Uppsala, Sweden, manufactures aesthetic and corrective products.
  • The Hortolândia site in the state of São Paulo, Brazil serves South America.

Governance

  • Flemming Ørnskov, chief executive officer
  • Thomas Dittrich chief financial officer
  • Adrian Murphy, head of global operations
  • Allison Pinkham, chief human resources officer

Notes and references

  1. "FY 2024 results" (Press release). Galderma. 6 March 2025.
  2. Weil, Jennifer (22 March 2024). "Galderma's Shares Soar on Stock Market Debut". Women's Wear Daily. https://wwd.com/beauty-industry-news/beauty-features/galderma-ipo-share-price-1236272965/. 
  3. "Galderma sets IPO price at top of range, or 53 CHF a share" (in en). Reuters. 2024-03-21. https://www.reuters.com/markets/deals/galderma-sets-final-price-ipo-top-range-2024-03-21/. 
  4. Nestlé
  5. 5.0 5.1 "Manufacturing" (in en). https://www.galderma.com/manufacturing. 
  6. 6.0 6.1 Preston, Quincy (2021-12-10). "Global Dermatology Innovator Galderma Moving U.S. Headquarters to Downtown Dallas » Dallas Innovates" (in en-US). https://dallasinnovates.com/global-dermatology-innovator-galderma-moving-u-s-headquarters-to-downtown-dallas/. 
  7. Heilprin, John (11 February 2014). "Nestlé exchanges stake in L'Oréal for Galderma". https://apnews.com/article/1a7c5cb4ebf743b391659ad9580a6981. 
  8. "At a glance" (in en). https://www.galderma.com/glance. 
  9. "UPDATE 2-Galderma bids $967 mln for Swedish implant firm Q-Med" (in en). Reuters. 13 December 2010. https://www.reuters.com/article/qmed-idUSLDE6BC0LA20101213. 
  10. Socha, Miles (11 February 2014). "L'Oréal to Buy 8% of Share Capital From Nestlé". WWD. https://www.wwd.com/beauty-industry-news/financial/loral-to-buy-8-of-share-capital-from-nestl-7438440?src=n/newsAlert/20140211-1. 
  11. "Ex-Shire CEO Flemming Ornskov emerges as Galderma CEO after $10B Nestlé spinout" (in en). 8 October 2019. https://www.fiercepharma.com/pharma/ex-shire-ceo-flemming-ornskov-emerges-as-galderma-ceo-after-10b-nestle-spinout. 
  12. Schuetze, Silke Koltrowitz, Arno (16 May 2019). "Nestle makeover advances with $10 billion sale of skin health unit" (in en). Reuters. https://www.reuters.com/article/us-nestle-m-a-skin-idUSKCN1SM0EI. 
  13. "Galderma to become the world's largest independent global dermatology company after completion of CHF 10.2 billion carve-out of Nestlé Skin Health" (in en). https://www.galderma.com/news/galderma-become-worlds-largest-independent-global-dermatology-company-after-completion-chf-102. 
  14. Farr, Emma-victoria (2021-11-29). "Galderma buys U.S. skincare firm Alastin ahead of potential Zurich IPO" (in en). Reuters. https://www.reuters.com/markets/europe/galderma-buys-us-skincare-firm-alastin-ahead-potential-zurich-ipo-2021-11-29/. 
  15. "Galderma announces positive results in two Phase III trials for liquid botulinum toxin A". June 2022. https://aestheticmed.co.uk/site/shownewsdetails/galderma-announces-positive-results-in-two-phase-i. 
  16. "Positive Phase 3 Results Announced for Nemolizumab Treatment of Atopic Dermatitis, Prurigo Nodularis" (in en). 2023-10-11. https://www.hcplive.com/view/positive-phase-3-results-announced-nemolizumab-treatment-atopic-dermatitis-prurigo-nodularis. 
  17. "An Efficacy and Safety Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis". June 2022. https://clinicaltrials.gov/ct2/show/NCT04501666. 
  18. "Skin care company Galderma seeks $2.3 bln in Swiss IPO". Reuters. 6 March 2024. https://www.reuters.com/markets/deals/skin-care-company-galderma-announces-23-billion-float-swiss-exchange-2024-03-06/. 
  19. Swetha Gopinath and Allegra Catelli (2024-03-22). "Galderma Surges in Debut, Bolstering Europe IPO Recovery". https://www.bloomberg.com/news/articles/2024-03-22/galderma-surges-in-trading-debut-bolstering-europe-ipo-recovery. 
  20. "Galderma Stock Surges in Debut on Swiss Stock Exchange" (in en). https://beautymatter.com/articles/galderma-stock-surges-in-debut. 
  21. 21.0 21.1 Dave Graham and John Revill (2024-03-22). "Skin care company Galderma's shares soar on market debut". https://www.reuters.com/business/retail-consumer/skin-care-company-galdermas-shares-soar-stock-market-debut-2024-03-22/. 
  22. "Galderma Announces Top-line Results from Phase 2 Clinical Dose-Escalating Study with Azzalure® / Dysport® (abobotulinumtoxinA)" (in en). 17 November 2020. https://www.businesswire.com/news/home/20201117005773/en/Galderma-Announces-Top-line-Results-from-Phase-2-Clinical-Dose-Escalating-Study-with-Azzalure%C2%AE-Dysport%C2%AE-abobotulinumtoxinA. 
  23. "Relfydess (relabotulinumtoxinA, purified Botulinum toxin type A)". 30 July 2024. https://www.tga.gov.au/resources/auspmd/relfydess-relabotulinumtoxina-purified-botulinum-toxin-type. 
  24. "Insights Into Positive Decision for Galderma's RelabotulinumtoxinA in Europe" (in en). 2024-08-12. https://www.dermatologytimes.com/view/insights-into-positive-decision-for-galderma-s-relabotulinumtoxina-in-europe. 
  25. Dunleavy, Kevin (2024-08-13). "FDA approves Galderma's Prurigo Nodularis treatment Nemluvio" (in en). https://www.fiercepharma.com/pharma/itching-leadership-therapeutic-dermatology-galderma-wins-fda-nod-nemluvio-treat-prurigo. 
  26. "FDA approves Nemolizumab to treat atopic dermatitis in patients 12 years and up" (in en). 2024-12-16. https://www.contemporarypediatrics.com/view/fda-approves-nemolizumab-to-treat-atopic-dermatitis-in-patients-12-years-and-up. 

See also

  • List of pharmaceutical companies
  • Pharmaceutical industry in Switzerland

Template:L'Oreal Brands Template:Pharmaceutical companies of Switzerland




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