c. 2300 BC: Unetice culture emerges in the modern day Czech Republic.
c. 2300 BC: Canal Bahr Yusuf (current name) is created when the waterway from the Nile to the natural lake (now Lake Moeris) is widened and deepened to create a canal.
c. 2300 BC – 2200 BC: "Head of a man from Nineveh" (modern Kuyunjik, Iraq) is made. It is now in Iraq Museum, Baghdad.
c. 2300 BC – 2184 BC: Disk of Enheduanna, from Ur, (modern Muqaiyir, Iraq) is made. It is now in University of Pennsylvania Museum of Archaeology and Anthropology, University of Pennsylvania, Philadelphia.
c. 2300–2250 BC, reigns of Pepi I Meryre and Merenre Nemtyemsaf I, beginning of Pepi II Neferkares' rule, all of the Sixth Dynasty of Egypt.
c. 2288 BC: "Queen Merye-ankhnes and her son Pepy II" is sculpted, Sixth dynasty of Egypt. The alabaster statuette is now at The Brooklyn Museum of Art, New York City .
c. 2285 BC: Enheduanna, high priestess of the moon god Nanna in Ur, was born.
c. 2254 BC – 2218 BC: Stela of Naram-Sin, probably from Sippar, discovered in Susa (modern Shush, Iran), is made. It is now in Musée du Louvre, Paris.
c. 2215 BC: A Guti army swept down from the Zagros Mountains and defeated the demoralized Akkadian army. They took Agade, the capital of Akkad, and destroyed it thoroughly.
c. July 2215 BC: Comet Hale-Bopp visits the inner solar system and would not return until the year AD 1997.