Isolated hyperCKemia

Isolated hyperCKemia
Other names	Asymptomatic hyperCKemia
Specialty	Medical genetics
Symptoms	None other than high levels of creatine kinase in the blood
Complications	None
Usual onset	Birth
Duration	Life-long
Causes	Genetic mutation
Diagnostic method	Genetic testing
Prevention	none
Medication	None required
Prognosis	Good
Frequency	Unknown, since almost all cases are asymptomatic

Isolated hyperCKemia is a benign^[1] genetic disorder which is characterized by high levels of creatine kinase (an enzyme) in the blood, usually, levels of CK in the blood of people with this disorder are 3 to 10 times higher than average. Unlike what most people experience when their CK blood levels are high,^[2] people with this disorder don't experience any symptoms, less commonly, people with isolated hyperCKemia have microscopic muscle cell abnormalities. This condition is a type of caveolinopathy since it is associated with the CAV3 gene, in chromosome 3.^[3]^[4] Although it is asymptomatic, people with this variant of hyperCKemia have an elevated risk of suffering from malignant hyperthermia.^[5]