NOX3
Topic: Biology
From Handwiki - Reading time: 2 min Generic protein structure example |
NADPH oxidase 3 is an enzyme that in humans is encoded by the NOX3 gene.[1][2]
Function
NADPH oxidases, such as NOX3, are plasma membrane-associated enzymes found in many cell types. They catalyze the production of superoxide by a 1-electron reduction of oxygen, using NADPH as the electron donor.[supplied by OMIM][2]
References
- ↑ "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5". Gene 269 (1–2): 131–40. May 2001. doi:10.1016/S0378-1119(01)00449-8. PMID 11376945.
- ↑ 2.0 2.1 "Entrez Gene: NOX3 NADPH oxidase 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50508.
Further reading
- "Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteins". J. Virol. 73 (2): 1447–52. 1999. doi:10.1128/JVI.73.2.1447-1452.1999. PMID 9882350.
- "NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells". Gene 254 (1–2): 237–43. 2000. doi:10.1016/S0378-1119(00)00258-4. PMID 10974555.
- "Nox3 regulation by NOXO1, p47phox, and p67phox". J. Biol. Chem. 279 (33): 34250–5. 2004. doi:10.1074/jbc.M400660200. PMID 15181005.
- "Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase". J. Neurosci. 24 (43): 9531–40. 2004. doi:10.1523/JNEUROSCI.3085-04.2004. PMID 15509740.
- "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators". J. Biol. Chem. 280 (24): 23328–39. 2005. doi:10.1074/jbc.M414548200. PMID 15824103.
- "Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases". Mol. Cell. Biol. 26 (6): 2160–74. 2006. doi:10.1128/MCB.26.6.2160-2174.2006. PMID 16507994. PMC 1430270. http://www.lib.kobe-u.ac.jp/repository/90000354.pdf.
- "Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3". Exp. Cell Res. 312 (17): 3413–24. 2006. doi:10.1016/j.yexcr.2006.07.003. PMID 16949073.
- "Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3". Biochem. J. 403 (1): 97–108. 2007. doi:10.1042/BJ20060819. PMID 17140397.
- "A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes". Am. J. Kidney Dis. 49 (3): 394–400. 2007. doi:10.1053/j.ajkd.2006.12.011. PMID 17336700.
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Original source: https://handwiki.org/wiki/NOX3
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Original source: https://handwiki.org/wiki/NOX3
Status: article is cached
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