Myeloproliferative neoplasm physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]
Overview[edit | edit source]
Patients with myeloproliferative neoplasm are usually well-appearing. Physical examination of patients with chronic myelogenous leukemia is usually remarkable for skin bruising, fever, splenomegaly, and lymphadenopathy.
Physical Examination[edit | edit source]
Common physical examination findings associated with myeloproliferative neoplasm include:[1][2][3][4]
Appearance of the Patient[edit | edit source]
- Patients are usually well-appearing at an early time point in the disease and ill-appearing at a later time point in the disease.
Vital Signs[edit | edit source]
Skin[edit | edit source]
HEENT[edit | edit source]
- Decreased vision acuity
- Mucosal pallor
Neck[edit | edit source]
Lungs[edit | edit source]
- Vesicular breath sounds
- Wheezing
Chest[edit | edit source]
- Axillary lymphadenopathy (usually painless)
Abdomen[edit | edit source]
- Splenomegaly
- Hepatomegaly
- Tenderness to palpation
Genitourinary[edit | edit source]
- Inguinal lymphadenopathy (usually painless)
- Scrotal swelling
- Priapism
References[edit | edit source]
- ↑ Agarwal MB, Malhotra H, Chakrabarti P, Varma N, Mathews V, Bhattacharyya J; et al. (2015). "Myeloproliferative neoplasms working group consensus recommendations for diagnosis and management of primary myelofibrosis, polycythemia vera, and essential thrombocythemia". Indian J Med Paediatr Oncol. 36 (1): 3–16. doi:10.4103/0971-5851.151770. PMC 4363847. PMID 25810569.
- ↑ Tefferi A (2006). "Classification, diagnosis and management of myeloproliferative disorders in the JAK2V617F era". Hematology Am Soc Hematol Educ Program: 240–245. PMID 17124067.
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/signs-and-symptoms/?region=ab
- ↑ Bittencourt RI, Vassallo J, Chauffaille Mde L, Xavier SG, Pagnano KB, Nascimento AC; et al. (2012). "Philadelphia-negative chronic myeloproliferative neoplasms". Rev Bras Hematol Hemoter. 34 (2): 140–9. doi:10.5581/1516-8484.20120034. PMC 3459391. PMID 23049404.
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