TIMELESS-interacting protein is a protein that in humans is encoded by the TIPIN gene .[ 1] [ 2] [ 3]
TIPIN has been shown to interact with Replication protein A1 .[ 4]
↑ Gotter AL (Aug 2003). "Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association". Journal of Molecular Biology . 331 (1): 167–76. doi :10.1016/S0022-2836(03)00633-8 . PMID 12875843 . ↑ Yoshizawa-Sugata N, Masai H (Jan 2007). "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint". The Journal of Biological Chemistry . 282 (4): 2729–40. doi :10.1074/jbc.M605596200 . PMID 17102137 . ↑ "Entrez Gene: TIPIN TIMELESS interacting protein" .↑ Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007). "The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" . Molecular and Cellular Biology . 27 (8): 3131–42. doi :10.1128/MCB.02190-06 . PMC 1899931 PMID 17296725 .
Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007). "The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" . Molecular and Cellular Biology . 27 (8): 3131–42. doi :10.1128/MCB.02190-06 . PMC 1899931 PMID 17296725 . Gotter AL, Suppa C, Emanuel BS (Feb 2007). "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors" . Journal of Molecular Biology . 366 (1): 36–52. doi :10.1016/j.jmb.2006.10.097 . PMC 4151250 PMID 17141802 . Chou DM, Elledge SJ (Nov 2006). "Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function" . Proceedings of the National Academy of Sciences of the United States of America . 103 (48): 18143–7. doi :10.1073/pnas.0609251103 . PMC 1654129 PMID 17116885 . Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Reports . 1 (3): 287–92. doi :10.1093/embo-reports/kvd058 . PMC 1083732 PMID 11256614 . Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research . 6 (9): 791–806. doi :10.1101/gr.6.9.791 . PMID 8889548 .
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