Categories
  • Small nuclear RNA
    •   Encyclosphere.org ENCYCLOREADER
      supported by EncyclosphereKSF

    Z12 small nucleolar RNA

    From Wikidoc - Reading time: 2 min
    Small nucleolar RNA SNORD104
    File:RF00289.jpg
    Predicted secondary structure and sequence conservation of SNORND104
    Identifiers
    SymbolSNORND104
    Alt. SymbolssnoZ12; Z12
    RfamRF00289
    Other data
    RNA typeGene; snRNA; snoRNA; CD-box
    Domain(s)Eukaryota
    GO0006396 0005730
    SO0001263
    LocusChr. 13 [1]
    PDB structuresPDBe

    Z12 small nucleolar RNA is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.[1] It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. Z12 snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]

    References[edit | edit source]

    1. ↑ 1.0 1.1 Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology. 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC 134041. PMID 12215523.

    External links[edit | edit source]


    This article is licensed under CC BY-SA 3.0.
    Original source: https://wikidoc.org/Z12 small nucleolar RNA
    Status: article is cached
    Encyclosphere.org EncycloReader is supported by the EncyclosphereKSF