Calcium-binding mitochondrial carrier protein SCaMC-1

SLC25A24
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4N5X, 4ZCU, 4ZCV
Identifiers
Aliases	SLC25A24, APC1, SCAMC-1, solute carrier family 25 member 24, SCAMC1
External IDs	OMIM: 608744 MGI: 1917160 HomoloGene: 92693 GeneCards: SLC25A24
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.3 Start 108,134,043 bp[1] End 108,200,849 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F3 Start 109,030,465 bp[2] End 109,075,773 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in rectum duodenum islet of Langerhans monocyte Achilles tendon endometrium smooth muscle tissue placenta gallbladder appendix Top expressed in left colon cumulus cell conjunctival fornix belly cord ileum endocardial cushion atrioventricular valve calvaria abdominal wall epithelium of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding ATP transmembrane transporter activity metal ion binding ADP transmembrane transporter activity transmembrane transporter activity Cellular component integral component of membrane membrane mitochondrion mitochondrial inner membrane Biological process regulation of cell death cellular response to calcium ion cellular response to oxidative stress mitochondrial transport transmembrane transport ATP transport ADP transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29957 229731 Ensembl ENSG00000085491 ENSG00000284468 ENSMUSG00000040322 UniProt Q6NUK1 Q8BMD8 RefSeq (mRNA) NM_013386 NM_213651 NM_172685 RefSeq (protein) NP_037518 NP_998816 NP_766273 Location (UCSC) Chr 1: 108.13 – 108.2 Mb Chr 3: 109.03 – 109.08 Mb PubMed search [3] [4]
Wikidata
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Calcium-binding mitochondrial carrier protein SCaMC-1 is a protein that in humans is encoded by the SLC25A24 gene.^[5]

Function[edit]

This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene.

References[edit]

Further reading[edit]

External links[edit]

• Overview of all the structural information available in the PDB for UniProt: Q6NUK1 (Human Calcium-binding mitochondrial carrier protein SCaMC-1) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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