Fluoroether E-1

Fluoroether E-1
Names
	Other names heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether, secondary hydrogen endcap
Identifiers
CAS Number	3330-15-2;
3D model (JSmol)	Interactive image;
ChemSpider	85066;
ECHA InfoCard	100.196.998
EC Number	236-236-8;
PubChem CID	94258;
CompTox Dashboard (EPA)	DTXSID8052017 ;
	InChI InChI=1S/C5HF11O/c6-1(2(7,8)9)17-5(15,16)3(10,11)4(12,13)14/h1H;
	SMILES C(C(F)(F)F)(OC(C(C(F)(F)F)(F)F)(F)F)F;
Properties
Chemical formula	C5HF11O
Molar mass	286.044 g·mol−1
Appearance	Colourless liquid
Density	1.538/cm³ (at 20 °C)
Boiling point	40–42 °C (104–108 °F; 313–315 K)
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H314, H335
Precautionary statements	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
NFPA 704 (fire diamond)	3 2 0
Safety data sheet (SDS)	[1]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Fluoroether E-1 (known chemically as heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether, is a chemical compound that is among the class of per- and polyfluoroalkyl substances (PFAS). This synthetic fluorochemical is used in the GenX process, and may arise from the degradation of GenX chemicals including FRD-903.^[2]^[3]

Production

The main production of Fluoroether E-1 is within the GenX process where FRD-903 (2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid) is used to generate (FRD-902) ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate, and Fluoroether E-1 (heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether).^[4]

Properties

Fluoroether E-1 is a colorless liquid that is practically insoluble in water. It is volatile and has a low boiling point.^[5]

References

^ "Heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether". pubchem.ncbi.nlm.nih.gov.
^ Zhang, Chuhui; McElroy, Amie C.; Liberatore, Hannah K.; Alexander, Nancy Lee M.; Knappe, Detlef R.U. (2022-05-17). "Stability of Per- and Polyfluoroalkyl Substances in Solvents Relevant to Environmental and Toxicological Analysis". Environmental Science & Technology. 56 (10): 6103–6112. Bibcode:2022EnST...56.6103Z. doi:10.1021/acs.est.1c03979. ISSN 0013-936X. PMC 9065217. PMID 34734715.
^ Wickersham, Lindsay (10 March 2023). "Characterization of PFAS air emissions from thermal application of fluoropolymer dispersions on fabrics". Journal of the Air & Waste Management Association. 73 (7): 533–552. Bibcode:2023JAWMA..73..533W. doi:10.1080/10962247.2023.2192009. PMC 10628852. PMID 36947591.
^ "Antwoord van Gedeputeerde Staten op vragen van W.A. Minderhout (PvdA)" [Answer from the Provincial Executive to questions from W.A. Minderhout (PvdA)] (PDF). Provincie Holland Zuid (in Dutch). 2015-09-15. Archived from the original (PDF) on 2018-02-08. Retrieved 2023-09-15.
^ "Heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether" (PDF). Apollo Scientific. 2023-10-07. Retrieved 2023-09-15.

[1] "Heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether". pubchem.ncbi.nlm.nih.gov.

[2] Zhang, Chuhui; McElroy, Amie C.; Liberatore, Hannah K.; Alexander, Nancy Lee M.; Knappe, Detlef R.U. (2022-05-17). "Stability of Per- and Polyfluoroalkyl Substances in Solvents Relevant to Environmental and Toxicological Analysis". Environmental Science & Technology. 56 (10): 6103–6112. Bibcode:2022EnST...56.6103Z. doi:10.1021/acs.est.1c03979. ISSN 0013-936X. PMC 9065217. PMID 34734715.

[3] Wickersham, Lindsay (10 March 2023). "Characterization of PFAS air emissions from thermal application of fluoropolymer dispersions on fabrics". Journal of the Air & Waste Management Association. 73 (7): 533–552. Bibcode:2023JAWMA..73..533W. doi:10.1080/10962247.2023.2192009. PMC 10628852. PMID 36947591.

[4] "Antwoord van Gedeputeerde Staten op vragen van W.A. Minderhout (PvdA)" [Answer from the Provincial Executive to questions from W.A. Minderhout (PvdA)] (PDF). Provincie Holland Zuid (in Dutch). 2015-09-15. Archived from the original (PDF) on 2018-02-08. Retrieved 2023-09-15.

[5] "Heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether" (PDF). Apollo Scientific. 2023-10-07. Retrieved 2023-09-15.

[1]

[2]

[3]

[4]

[5]