GNG7

GNG7
Identifiers
Aliases	GNG7, G protein subunit gamma 7, HG3B
External IDs	OMIM: 604430; MGI: 95787; HomoloGene: 31293; GeneCards: GNG7; OMA:GNG7 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	2,702,694 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,850,779 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; caudate nucleus; ; putamen; ; inferior ganglion of vagus nerve; ; external globus pallidus; ; C1 segment; ; ventral tegmental area; ; subthalamic nucleus; ; superior vestibular nucleus; ; Amygdala;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; globus pallidus; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; subiculum; ; hippocampus proper; ; Temporal Lobe; ; Amygdala;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; GTPase activity; G-protein beta-subunit binding;
Cellular component	heterotrimeric G-protein complex; plasma membrane; extracellular exosome; membrane; G-protein beta/gamma-subunit complex;
Biological process	G protein-coupled receptor signaling pathway; cellular response to glucagon stimulus; regulation of G protein-coupled receptor signaling pathway; signal transduction; behavioral fear response; receptor guanylyl cyclase signaling pathway; locomotory behavior; regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Orthologs
	2788
	14708
	ENSG00000176533
	ENSMUSG00000048240
	O60262
	Q61016
	NM_052847
	NM_001038655; NM_010319
	NP_443079
	NP_001033744; NP_034449; NP_001393192; NP_001393193
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 is a protein that in humans is encoded by the GNG7 gene.^[5]^[6]

Interactions

GNG7 has been shown to interact with GNB5.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000176533 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048240 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shibata K, Mori M, Tanaka S, Kitano S, Akiyoshi T (Jun 1998). "Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer". Biochem. Biophys. Res. Commun. 246 (1): 205–9. doi:10.1006/bbrc.1998.8581. PMID 9600093.
^ "Entrez Gene: GNG7 guanine nucleotide binding protein (G protein), gamma 7".
^ Yan K, Kalyanaraman V, Gautam N (Mar 1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.

Ueda N, Iñiguez-Lluhi JA, Lee E, Smrcka AV, Robishaw JD, Gilman AG (1994). "G protein beta gamma subunits. Simplified purification and properties of novel isoforms". J. Biol. Chem. 269 (6): 4388–95. doi:10.1016/S0021-9258(17)41792-3. PMID 8308009.
Yan K, Kalyanaraman V, Gautam N (1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000176533 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048240 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9600093-5] Shibata K, Mori M, Tanaka S, Kitano S, Akiyoshi T (Jun 1998). "Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer". Biochem. Biophys. Res. Commun. 246 (1): 205–9. doi:10.1006/bbrc.1998.8581. PMID 9600093.

[entrez-6] "Entrez Gene: GNG7 guanine nucleotide binding protein (G protein), gamma 7".

[pmid8636150-7] Yan K, Kalyanaraman V, Gautam N (Mar 1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.

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GNG7

Interactions

References

Further reading