From Wikipedia - Reading time: 4 min
Moroxydine
Names
IUPAC name
N -(Diaminomethylidene)morpholine-4-carboximidamide
Other names
Moroxidine
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard
100.020.994
EC Number
KEGG
UNII
InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
N Key: KJHOZAZQWVKILO-UHFFFAOYSA-N
N InChI=1/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
Key: KJHOZAZQWVKILO-UHFFFAOYAH
Properties
Chemical formula
C6 H13 N5 O
Molar mass
171.20 g/mol
Pharmacology
ATC code
J05AX01 (WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Moroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses.[1] Structurally moroxydine is a heterocyclic biguanidine.
It was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings.[2]
References [ edit]
Wikispecies has information related to
Moroxydine .
RNA virus antivirals (primarily J05, also S01AD and D06BB)
Hepatitis C
NS3/4A protease inhibitors (–previr)
Asunaprevir
Boceprevir‡
Ciluprevir§
Danoprevir†
Faldaprevir‡
Glecaprevir
Grazoprevir
Narlaprevir
Paritaprevir
Simeprevir
Sovaprevir†
Telaprevir‡
Vaniprevir
Vedroprevir§
Voxilaprevir
NS5A inhibitors (–asvir)
Daclatasvir#
Elbasvir
Ledipasvir
Odalasvir†
Ombitasvir
Pibrentasvir
Ravidasvir†
Ruzasvir†
Samatasvir†
Velpatasvir
NS5B RNA polymerase inhibitors (–buvir)
Beclabuvir†
Bemnifosbuvir†
Dasabuvir#
Deleobuvir§
Filibuvir§
GS-6620§
IDX-184§
Setrobuvir§
Sofosbuvir#
Tegobuvir§
TMC-647055§
Radalbuvir†
Uprifosbuvir†
Combination drugs
Elbasvir/grazoprevir
Glecaprevir/pibrentasvir
Ledipasvir/sofosbuvir#
Ombitasvir/paritaprevir/ritonavir#
Sofosbuvir/daclatasvir
Sofosbuvir/velpatasvir#
Sofosbuvir/velpatasvir/voxilaprevir
Hepatitis D Picornavirus Anti-influenza agents
Baloxavir marboxil
Pimodivir†
Umifenovir
adamantane derivatives/M2 inhibitors (Adapromine
Amantadine
Rimantadine)
neuraminidase inhibitors/release phase (Oseltamivir#
Zanamivir
Peramivir, Laninamivir† )
Multiple/general
Interferon
Interferon alfa 2b
Peginterferon alfa-2a#
Peginterferon alfa-2b#
Multiple/unknown
CMX521§
EICAR§
Ensitrelvir†
Favipiravir
Galidesivir†
GS-441524§
Remdesivir
Lufotrelvir
MK-608§
Mericitabine†
Merimepodib§
Molnupiravir
Moroxydine
Nirmatrelvir† (+ritonavir)†
NITD008§
Presatovir†
Ribavirin#
Taribavirin†
Triazavirin
Valopicitabine†
# WHO-EM
‡ Withdrawn from market
Clinical trials:
† Phase III
§ Never to phase III
DNA virus antivirals (primarily J05, also S01AD and D06BB)
Baltimore I
Herpesvirus
DNA-synthesis inhibitor
TK activated
Purine analogue
guanine (Aciclovir# /Valaciclovir
Ganciclovir/Valganciclovir#
Penciclovir/Famciclovir)
Pyrimidine analogue
uridine (Idoxuridine
Trifluridine (+tipiracil)
Edoxudine)
thymine
Brivudine
FV-100†
Sorivudine‡
Not TK activated
Other
Amenamevir
Docosanol
Letermovir
Maribavir
early protein (Fomivirsen‡ )
Tromantadine
HPV/MC
Imiquimod/Resiquimod
Podophyllotoxin
Vaccinia Poxviridae
Hepatitis B (VII)
Nucleoside analogues/NARTIs: Entecavir#
Lamivudine
Lobucavir†
Telbivudine
Clevudine
Nucleotide analogues/NtRTIs: Adefovir
Tenofovir disoproxil
Tenofovir alafenamide
Multiple/general
Nucleic acid inhibitors Interferon
Interferon alfa 2b
Peginterferon alfa-2a
Multiple/unknown
# WHO-EM
‡ Withdrawn from market
Clinical trials:
† Phase III
§ Never to phase III
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