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    HU大麻素列表

    From Wikipedia_zh - Reading time: 1 min

    耶路撒冷希伯來大學（Hebrew University）的拉斐尔·梅舒朗研究小组合成了上百种大麻素，其中一些是[1]：

    大麻素及其Ki值(Ki是化合物对大麻素1型受体（CB1）或大麻素2型受体（CB2）的结合亲和力)
    名称 类别 分子式 Ki/nM (CB1) Ki/nM (CB2) 选择性 结构
    HU-210 二苯并吡喃 C25H38O3 0.23 CB1
    HU-211 二苯并吡喃 C25H38O3 CB2
    HU-239 二苯并吡喃 C25H36O4
    HU-243 二苯并吡喃 C25H40O3
    HU-308 联苯 C27H42O3
    HU-320 联苯 C25H36O4
    HU-331 联苯 C21H28O3
    HU-336 二苯并吡喃 C21H28O3
    HU-345 二苯并吡喃 C21H24O3
    HU-474 联苯[2] C21H29FO2
    HU-910 联苯[2] C27H42O3 1400[3] 6[3] CB2

    参见[编辑]

    • AM大麻素列表
    • CP大麻素列表
    • JWH大麻素列表
    • 杂项设计师大麻素列表（英语：List of miscellaneous designer cannabinoids）

    参考文献[编辑]

    1. ^ Howlett, AC; Champion, TM; Wilken, GH; Mechoulam, R. Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor. Neuropharmacology. February 1990, 29 (2): 161–5. PMID 2158635. S2CID 28602221. doi:10.1016/0028-3908(90)90056-W. 
    2. ^ 2.0 2.1 Dos Santos Pereira, M; Maitan Santos, B; Gimenez, R; Guimarães, FS; Raisman-Vozari, R; Del Bel, E; Michel, PP. The two synthetic cannabinoid compounds 4'-F-CBD and HU-910 efficiently restrain inflammatory responses of brain microglia and astrocytes.. Glia. 2024-03, 72 (3): 529–545. PMID 38013496. doi:10.1002/glia.24489. 
    3. ^ 3.0 3.1 Horváth, B; Magid, L; Mukhopadhyay, P; Bátkai, S; Rajesh, M; Park, O; Tanchian, G; Gao, RY; Goodfellow, CE; Glass, M; Mechoulam, R; Pacher, P. A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.. British journal of pharmacology. 2012-04, 165 (8): 2462–78. PMID 21449982. doi:10.1111/j.1476-5381.2011.01381.x. 
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