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    Amir Sagi

    From Wikitia - Reading time: 4 min
    Amir Sagi
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    Born (1956-05-22) May 22, 1956 (age 67)
    Beit Zait, near Jerusalem, Israel
    NationalityIsrael
    Alma materHebrew University of Jerusalem
    OccupationProfessor

    Amir Sagi (born May 22, 1956) is an Israeli professor of life sciences, recognized for his contributions to crustacean biology, physiology, functional genomics, sexual differentiation and biotechnology.

    Early life and education[edit]

    Sagi was born on May 22, 1956, in Beit Zait, near Jerusalem, Israel. He completed his B.Sc., M.Sc., and Ph.D. at the Hebrew University of Jerusalem.[1]

    Research and career[edit]

    The work conducted by Sagi and his research team has made significant contributions to the field of decapod crustacean biology, particularly in the areas of genetics and sex differentiation. Their research led to the discovery of the insulin-like androgenic hormone (IAG),[2] a crucial secretion of the androgenic gland in decapod crustaceans.[3] This discovery has been pivotal in understanding the processes of sex differentiation and the signaling cascade associated with it, shedding light on the biological development of these species.

    Further extending the implications of their findings, Sagi's team has developed biotechnologies for the production of monosex prawns.[4]

    Patents[edit]

    Sagi has obtained patents for his inventions including Insulin-like gene of prawns and uses thereof (AU2009211046B9), Delivery peptides and methods of using the same (US20220204563A1), Stable amorphous calcium carbonate comprising synthetic phosphorylated peptides (US10328100B2),Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders (US10688124B2), Composition comprising crustacean gastrolith components and its use (US8728533B2), Orally administrable compositions comprising stable amorphous calcium carbonate (ES2447747T3), Denitrification treatment system and method (WO2007138604A3), Sex-linked genomic marker for crayfish and uses thereof (WO2019058371A1),[5] Insulin-like gene in prawns and uses thereof (WO2009098683A2), Functional sex-reversal of decapod crustacean females (AU2015346969A1), WW homogametic male decapod crustacean and methods of using the same (US10791721B2), Insulin-like gene in prawns and uses thereof (US20120073508A1).<ref>

    References[edit]

    1. ↑ "Amir Sagi". Israeli Research Community Portal. Retrieved 2024-02-08.
    2. ↑ Ventura, Tomer; Sagi, Amir (2012-11-01). "The insulin-like androgenic gland hormone in crustaceans: From a single gene silencing to a wide array of sexual manipulation-based biotechnologies". Biotechnology Advances. Special issue on ACB 2011. 30 (6): 1543–1550. doi:10.1016/j.biotechadv.2012.04.008. ISSN 0734-9750. PMID 22561950.
    3. ↑ Sagi, Amir; Snir, Eviatar; Khalaila, Isam (January 1997). "Sexual differentiation in decapod crustaceans: role of the androgenic gland". Invertebrate Reproduction & Development. 31 (1–3): 55–61. Bibcode:1997InvRD..31...55S. doi:10.1080/07924259.1997.9672563. ISSN 0792-4259.
    4. ↑ "Monosex culture of prawns through temporal androgenic gene silencing - Responsible Seafood Advocate". Global Seafood Alliance. 2013-11-02. Retrieved 2024-02-08.
    5. ↑ "Sex-linked genomic marker for crayfish and uses thereof-AU2018336160A1". PatentGuru. Retrieved 2024-02-08.

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