ACTH-secreting tumor

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

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An ACTH secreting tumor is a type of pituitary adenoma which produces ACTH.

Pathophysiology

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The tumor stains basophilic on pathologic examination. The excess production of ACTH by the tumor results in Cushing's syndrome.

Diagnosis

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Pituitary adenomas may grow and compress adjacent structures, most commonly causing a bitemporal hemianopsia due to compression of the optic chiasm. Lateral extension into the cavernous sinuses can result in cranial nerve palsies.

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