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Acrokeratoelastoidosis of Costa

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Acrokeratoelastoidosis of Costa
Classification and external resources
OMIM 101850
DiseasesDB 29804
eMedicine article/1113926 

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview[edit | edit source]

Acrokeratoelastoidosis of Costa (also known as "Keratoelastoidosis marginalis"[1]) is a familial condition characterized by multiple keratotic papules on the dorsum of the hands and feet, palms, soles, in which electron microscopy shows rarified, abnormal elastic tissue.[2]:993[3]:214

It was characterized in 1953.[4]

Diagnosis[edit | edit source]

Physical Examination[edit | edit source]

Skin[edit | edit source]

Feet[edit | edit source]

Treatments such as liquid nitrogen, salicylic acid, tretinoin, and prednisone have been tried, though with limited success.[6]

See also[edit | edit source]

References[edit | edit source]

  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  2. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
  3. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  4. Costa OG (1953). "Akrokerato-elastoidosis; a hitherto undescribed skin disease". Dermatologica. 107 (3): 164–8. doi:10.1159/000256794. PMID 13116681.
  5. 5.0 5.1 5.2 5.3 5.4 "Dermatology Atlas".
  6. Zhai Z, Yang X, Hao F (2006). "Acrokeratoelastoidosis". Eur J Dermatol. 16 (2): 201–2. PMID 16613753.

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