Amyloidosis CT

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[3]Sabawoon Mirwais, M.B.B.S, M.D.[4]

Overview[edit | edit source]

CT can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis.

CT[edit | edit source]

In hepatic amyloidosis the CT scan findings may include:

• Liver enlargement with heterogeneous decreased attenuation
• Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
• Parenchyma calcification (rare)

In renal amyloidosis the CT findings may include:

• Kidney enlargement with heterogeneous decreased attenuation
• Parenchyma calcification (rare)

In cardiac amyloidosis the CT findings may include^[1]:

• Heart enlargement with heterogeneous decreased attenuation
• Cardiac calcifications
• Pericardial effusion (rare)

Images[edit | edit source]

References[edit | edit source]

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