Ankylosing spondylitis causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview[edit | edit source]

Ankylosing spondylitis is an inflammatory disease that in overtime it causes some of the vertebrae in your spine to fuse.Because of the fusion the spine less flexible and the patients present with hunched-forward posture. It can be difficult to breathe deeply when the ribs are involved.The most common cause of ankylosing spondylitis is involvement of gene HLA B27.

Causes[edit | edit source]

Common Causes

• Heredity
  • People who are positive for HLA-B27 gene are more prone to develop ankylosing spondylitis.^[1][2]
• Sex
  • When compared to women, men are more likely to develop ankylosing spondylitis.
• Age
  • Most commonly seen in adolescence.^[3]
• Race
  • Ankylosing spondylitis is more common in Native American tribes.^[4]

References[edit | edit source]

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