Autoimmune hemolytic anemia screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2], Irfan Dotani [3]

Screening for autoimmune hemolytic anemia is not currently done routinely.

• Screening for autoimmune hemolytic anemia is not currently done routinely.
• The incidence of autoimmune hemolytic anemia is low enough such that screening measures are not indicated.
• However, screening is done for other conditions associated with hemolytic anemia, such as sickle cell disease.^[1]
• One important manifestation of sickle cell disease is hyperhemolytic crisis, in which there is massive hemolysis.
• The United States and the United Kingdom have formal screening processes in place for sickle cell disease for newborns.
• Screening for sickle cell disease can prevent early childhood morbidity and mortality.
• Less developed countries, such as countries in Africa, do not have formal screening measures for sickle cell disease in place.^[1]

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