Bipolar disorder epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nuha Al-Howthi, MD[2]
Overview[edit | edit source]
The estimated lifetime prevalence of bipolar disorder among adults worldwide is 1 to 3 percent, and the lifetime prevalence of bipolar I and bipolar II disorder was 2.8 percent. The mean age of onset for bipolar I disorder is 18 years and for bipolar II disorder 20 years. The one-year prevalence of bipolar I disorder in people aged 65 years and older is approximately 0.4 percent and the lifetime rate is 0.8 percent. These rates were less than rates in younger individuals.
Epidemiology and demographics[edit | edit source]
- The estimated lifetime prevalence of bipolar disorder among adults worldwide is 1 to 3 percent[1], and the lifetime prevalence of bipolar I and bipolar II disorder was 2.8 percent[2]
- The mean age of onset for bipolar I disorder is 18 years and for bipolar II disorder 20 years[3]. The ratio of men to women who develop bipolar disorder is approximately 1:1.
- In the United States, the estimated lifetime prevalence of bipolar I disorder was 1 percent, and bipolar II disorder 1.1 percent. The mean age of onset for bipolar I and bipolar II disorder was 18 and 20 years.[4]
- Bipolar disorder is the 18th leading cause of disability in the United States.[5]
- Individuals with manic or hypomanic episodes, psychosocial functioning is severely impaired in 70 percent; in 90 percent of the affected individuals functioning is severely impaired during episodes of major depression.[4]
- The one-year prevalence of bipolar I disorder in people aged 65 years and older is approximately 0.4 percent and the lifetime rate is 0.8 percent. These rates were less than rates in younger individuals.[6]
- Geriatric bipolar patients are predominantly female; 69 percent of late-life bipolar patients were women.[7]
- The prevalence of bipolar spectrum disorders in children and adolescents is approximately 2 percent.[8] However it is not well established because several factors make the diagnosis of bipolar disorder in pediatric complex and controversial.[9]
- Pediatric bipolar disorder is characterized by high rates of comorbidity.[8]
- Community studies suggest that the prevalence of bipolar disorder may be greater among adolescents (age 13 to 18 years) than children (age ≤12 years)[10][11]
References[edit | edit source]
- ↑ Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ; et al. (2014). "A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders". JAMA Psychiatry. 71 (5): 573–81. doi:10.1001/jamapsychiatry.2014.16. PMID 24806211. Review in: Evid Based Ment Health. 2015 Feb;18(1):12
- ↑ Kessler RC, Ormel J, Petukhova M, McLaughlin KA, Green JG, Russo LJ; et al. (2011). "Development of lifetime comorbidity in the World Health Organization world mental health surveys". Arch Gen Psychiatry. 68 (1): 90–100. doi:10.1001/archgenpsychiatry.2010.180. PMC 3057480. PMID 21199968.
- ↑ Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA; et al. (2011). "Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative". Arch Gen Psychiatry. 68 (3): 241–51. doi:10.1001/archgenpsychiatry.2011.12. PMC 3486639. PMID 21383262.
- ↑ 4.0 4.1 Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M; et al. (2007). "Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication". Arch Gen Psychiatry. 64 (5): 543–52. doi:10.1001/archpsyc.64.5.543. PMC 1931566. PMID 17485606.
- ↑ Murray CJ, Atkinson C, Bhalla K, Birbeck G, Burstein R, Chou D; et al. (2013). "The state of US health, 1990-2010: burden of diseases, injuries, and risk factors". JAMA. 310 (6): 591–608. doi:10.1001/jama.2013.13805. PMC 5436627. PMID 23842577.
- ↑ Blanco C, Compton WM, Saha TD, Goldstein BI, Ruan WJ, Huang B | display-authors=etal (2017) Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III. J Psychiatr Res 84 ():310-317. DOI:10.1016/j.jpsychires.2016.10.003 PMID: 27814503
- ↑ Seedat S, Scott KM, Angermeyer MC, Berglund P, Bromet EJ, Brugha TS; et al. (2009). "Cross-national associations between gender and mental disorders in the World Health Organization World Mental Health Surveys". Arch Gen Psychiatry. 66 (7): 785–95. doi:10.1001/archgenpsychiatry.2009.36. PMC 2810067. PMID 19581570.
- ↑ 8.0 8.1 Van Meter AR, Moreira AL, Youngstrom EA (2011). "Meta-analysis of epidemiologic studies of pediatric bipolar disorder". J Clin Psychiatry. 72 (9): 1250–6. doi:10.4088/JCP.10m06290. PMID 21672501.
- ↑ Grande I, Berk M, Birmaher B, Vieta E (2016). "Bipolar disorder". Lancet. 387 (10027): 1561–1572. doi:10.1016/S0140-6736(15)00241-X. PMID 26388529.
- ↑ Van Meter AR, Moreira AL, Youngstrom EA (2011). "Meta-analysis of epidemiologic studies of pediatric bipolar disorder". J Clin Psychiatry. 72 (9): 1250–6. doi:10.4088/JCP.10m06290. PMID 21672501.
- ↑ Douglas J, Scott J (2014). "A systematic review of gender-specific rates of unipolar and bipolar disorders in community studies of pre-pubertal children". Bipolar Disord. 16 (1): 5–15. doi:10.1111/bdi.12155. PMID 24305108.
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